725277-97-4Relevant academic research and scientific papers
Synthesis of diphenylcarbazoles as cytotoxic DNA binding agents
Jacquemard, Ulfich,Routier, Sylvain,Tatibouet, Arnaud,Kluza, Jerome,Laine, William,Bal, Christine,Bailly, Christian,Merour, Jean-Yves
, p. 1476 - 1483 (2004)
We report the synthesis or a series of novel diphenylcarbazoles designed to interact with DNA. The compounds bearing two or three dimethylaminoalkyloxy side chains were found to bind much more tightly to DNA, preferentially at AT-rich sites, than the corr
