7253-25-0Relevant academic research and scientific papers
Tyrosyl-DNA Phosphodiesterase i Inhibitors from the Australian Plant Macropteranthes leichhardtii
Tian, Li-Wen,Feng, Yunjiang,Tran, Trong D.,Shimizu, Yoko,Pfeifer, Tom,Forster, Paul I.,Quinn, Ronald J.
, p. 1756 - 1760 (2015)
Mass-directed isolation of the CH2Cl2/MeOH extract from the bark of an Australian plant, Macropteranthes leichhardtii, resulted in the purification of a new phenylpropanoid glucoside, macropteranthol (1), together with four known analogues (2-5). The structure of compound 1 was elucidated by NMR and MS data analyses and quantum chemical calculations. Compounds 3 and 5 showed inhibitory activity against tyrosyl-DNA phosphodiesterase I with IC50 values of ～1.0 μM.
New oligomeric proanthocyanidins from Alhagi pseudalhagi
Alimova,Nishanbaev,Vdovin,Abdullaev,Aripova
experimental part, p. 352 - 356 (2010/10/03)
Two new oligomeric proanthocyanidin glucosides were isolated from the aerial part and roots of Alhagi pseudalhagi. Their structures and relative configurations were elucidated as 7-O-β-D-Glc p→6 galloyl-(+)catechin-(4α-8)-(+)-catechin-(4α-8)-(-
New oligomeric proanthocyanidin glycosides platanoside-A and platanoside-B from Platanus orientalis trunk bark
Nishanbaev,Khidyrova,Vdovin,Abdullaev,Shakhidoyatov,Aripov
experimental part, p. 357 - 362 (2010/10/03)
Two new oligomeric proanthocyanidin glycosides were isolated from trunk bark of Platanus orientalis. Their structures and relative configurations were found to be 7-O-β-D-Glcp-(-)-epicatechin-(4β-8)-(-)- epicatechin(4β-8)-(-)-epicatechin-3-O-gallate (plat
Ericifolin: An eugenol 5-O-galloylglucoside and other phenolics from Melaleuca ericifolia
Hussein,Hashim,El-Sharawy,Seliem,Linscheid,Lindequist,Nawwar
, p. 1464 - 1470 (2008/09/19)
Ericifolin, an eugenol 5-O-β-(6′-O-galloylglucopyranoside) possessing the naturally unknown phenolic moiety, 5-hydroxyeugenol, together with the two new phenolics, 2-O-p-hydroxybenzoyl-6-O-galloyl-(α/β)-4C1-glucopyranose and 3-methoxyellagic acid 4-O-rhamnopyranoside have been isolated from the antibacterial leaves extract of Melaleuca ericifolia. In addition, 19 known phenolics were also separated and characterized. All structures were elucidated on the basis of analysis of 1H, 13C NMR, HMQC, HMBC and FTMS spectral data.
Synthesis of gallotannins
He, Qiang,Shi, Bi,Yao, Kai,Luo, Yi,Ma, Zhihong
, p. 245 - 250 (2007/10/03)
As a contribution to the synthesis of gallotannins, four O-galloyl-D-glucoses (3-O-, 6-O-, 3,6-di-O-, 3,4,6-tri-O-galloyl-D-glucose) have been prepared by the reaction of tri-O-benzylgalloyl chloride and partially protected glucose derivatives (1,2-O-, an
BIOSYNTHESIS OF 1,2,3,6-TETRA-O-GALLOYL-β-D-GLUCOSE
Hagenah, Sigrid,Gross, Georg G.
, p. 637 - 642 (2007/10/02)
An enzyme that catalysed the β-glucogallin (1-O-galloyl-β-D-glucose)-dependent galloylation of 1,2,6-tri-O-galloyl-β-D-glucose to 1,2,3,6-tetra-O-galloyl-β-D-glucose was partially purified from leaves of the oak (Quercus robur).This acyltransferase had a Mr of ca 380000, and pH and temperature optima of 6.0 and 55 deg, respectively, and was most stable between pH 4.0 and 6.5.In addition to the natural substrates β-glucogallin (donor) and 1,2,6-trigalloylglucose (acceptor), 1,3,6-trigalloylglucose (which is not an intermediate in the biosynthesis of hydrolysable tannins in oak and sumac) was an equally efficient acceptor molecule; in both cases, 1,2,3,6-tetragalloylglucose was the reaction product.Based on the physiological role of this new enzyme, the systematic name "β-glucogallin: 1,2,6-tri-O-galloyl-β-D-glucose 3-O-galloyltransferase" (EC.2.3.1.-) is proposed. Key Word Index - Quercus robur (Q. pedunculata); Fagaceae; pedunculate oak; Rhus typhina; Anacardiaceae; staghorn sumac; biosynthesis; hydrolysable tannins; galloyltransferase; β-glucogallin; 1,2,6-tri-O-galloyl-β-D-glucose; 1,2,3,6-tetra-O-galloyl-β-D-glucose.
