7253-52-3Relevant academic research and scientific papers
in Water : Organocatalyzed Diastereoselective Multicomponent Reactions toward 2-Azapyrrolizidine Alkaloid Scaffolds
Rajarathinam, Balakrishnan,Kumaravel, Kandhasamy,Vasuki, Gnanasambandam
supporting information, p. 455 - 463 (2017/07/15)
Synthesis of the 2-aza analogues of pyrrolizidine and spirooxindole-2-azapyrrolizidine hybrid, a spiro-tetracyclic scaffold possessing multiple contiguous stereocenters, by an exclusive regio-, chemo-, and diastereoselective multicomponent reaction in water is reported. This logical and didactical tactic has integrated the principles of an ideal organic synthesis, privileged substructure-based diversity-oriented synthesis, and biology-oriented synthesis to access hybrid heterocyclic scaffolds.
A heterocyclic compound and use thereof
-
Paragraph 0117; 0124-0126, (2017/11/16)
The invention relates to a heterocyclic compound as shown in a general formula I which is described in the specification and application of the heterocyclic compound as a plant disease resistance activator. In the general formula I, R1 is selected from the group consisting of hydrogen, a C1-C6 alkyl group and a C3-C6 cycloalkyl group, R2 is selected from the group consisting of hydrogen, a C1-C6 alkyl group, a substituted or non-substituted C1-C14 aryl group and a five-membered or six-membered heterocycle containing nitrogen, oxygen and sulfur, and n is a positive integer in a range of 2 to 4. The compound provided by the invention inhibits pathogens through inducing a plant to generate disease resistance against pathogens instead of directly killing or inhibiting pathogens. The compound provided by the invention has the advantages of systematicness, persistence, broad spectrum activity, security, etc., enables the usage amount of highly toxic pesticides to be reduced and is friendly to the environment; so the compound has great industrial and commercial prospects and a great market value.
Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents
Habib, Monica M. W.,Abdelfattah, Mohamed A. O.,Abadi, Ashraf H.
, p. 868 - 874 (2015/12/24)
Eighteen new 5-benzylidene-3-(4-arylpiperazin-1-ylmethyl)-2-thioxo-imidazolidin-4-ones were designed as hybrid structures from previously reported anticonvulsant compounds, synthesized and tested for anticonvulsant activity. Initial anticonvulsant screeni
Glycine derivatives of imidazolones as potential ligands of glycine binding site of NMDA receptors. Part 1
Kiec-Kononowicz, Katarzyna,Karolak-Wojciechowska, Janina,Handzlik, Jadwiga
, p. 381 - 388 (2007/10/03)
The series of glycine derivatives of diphenyl or (un)substituted arylidene imidazolones was designed and obtained as potential ligands of the glycine binding site of NMDA receptors. The compounds were evaluated in vitro for their affinity to the glycine b
