7253-67-0 Usage
Uses
Used in Pharmaceutical Industry:
2-phenyl-2-piperidinoacetamide is used as a chemical intermediate for the synthesis of various drugs and pharmaceutical products. Its versatile structure allows for the development of new medications with potential therapeutic benefits.
Used as an Analgesic and Anesthetic:
PPAA is used as an analgesic to relieve pain and as an anesthetic to induce a loss of sensation, particularly in local anesthetic applications. Its properties are currently being studied to determine its full potential in these areas.
Used in Neurological Disorder Treatment:
2-phenyl-2-piperidinoacetamide is being investigated for its potential use in the treatment of neurological disorders. Its specific role and efficacy in this context are under research to establish its therapeutic value.
Used as an Anti-Inflammatory Agent:
PPAA is also being explored for its potential as an anti-inflammatory agent. 2-phenyl-2-piperidinoacetamide's ability to reduce inflammation is currently a subject of study to assess its suitability for various inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 7253-67-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7253-67:
(6*7)+(5*2)+(4*5)+(3*3)+(2*6)+(1*7)=100
100 % 10 = 0
So 7253-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H18N2O/c14-13(16)12(11-7-3-1-4-8-11)15-9-5-2-6-10-15/h1,3-4,7-8,12H,2,5-6,9-10H2,(H2,14,16)
7253-67-0Relevant academic research and scientific papers
Postcondensation modifications of Ugi four-component condensation products: 1-Isocyanocyclohexene as a convertible isocyanide. Mechanism of conversion, synthesis of diverse structures, and demonstration of resin capture
Keating,Armstrong
, p. 2574 - 2583 (2007/10/03)
The concept of a 'universal isocyanide' that enables postcondensation modification of Ugi four-component condensation products is introduced. This strategy is suited for the synthesis of libraries. By using 1-isocyanocyclohexene as the isocyanide input in the Ugi reaction, the product cyclohexenamides can be converted to a variety of products. From the original α-(acylamino) amides, new carboxylic acids, esters, and thioesters are produced from acid-activated conversion of the cyclohexenamide moiety. It has been determined that the intermediate in conversion of this type is an oxazolinium-5-one (munchnone) that reacts with many nucleophiles to yield the products above. The munchnone can also undergo cycloaddition with acetylenic dipolarophiles to form pyrroles. Through internal nucleophilic attack, Ugi products are shown to convert to a protected monosaccharide derivative and to 1,4-benzodiazepine-2,5-diones. All of the conversions described consist of a single step. Resin capture of Ugi products is demonstrated, in which a solution condensation reaction is followed by trapping of the products onto solid support resin. Both the trapping step and subsequent cleavage of products from the resin occur in very high yield.
