72541-00-5 Usage
Uses
Used in Medicinal Chemistry:
(5S,3R)-5-(3-Furyl)-3',4,5,5',5'aβ,7',8',8'aα-octahydro-7'α-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione is used as a structural component in the development of new pharmaceuticals for various therapeutic applications. Its unique spirocyclic framework and chiral configuration contribute to its potential as a key building block in the synthesis of bioactive molecules.
Used in Organic Synthesis:
In the field of organic synthesis, (5S,3R)-5-(3-Furyl)-3',4,5,5',5'aβ,7',8',8'aα-octahydro-7'α-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione serves as a valuable intermediate or starting material for the synthesis of more complex organic molecules. Its furan and naphthofuran ring systems, along with the furan-2,2'-dione moiety, provide a rich platform for further chemical modifications and functionalization.
Used in Chemical Biology:
(5S,3R)-5-(3-Furyl)-3',4,5,5',5'aβ,7',8',8'aα-octahydro-7'α-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione is utilized in chemical biology as a probe to study the interactions between small molecules and biological targets. Its unique structure allows for the investigation of molecular recognition, binding affinity, and potential biological activities, which can lead to the discovery of new bioactive compounds or the elucidation of biological pathways.
Used in Drug Design and Development:
In the pharmaceutical industry, (5S,3R)-5-(3-Furyl)-3',4,5,5',5'aβ,7',8',8'aα-octahydro-7'α-methylspiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione is employed as a lead compound in drug design and development. Its structural features can be optimized to enhance potency, selectivity, and pharmacokinetic properties, ultimately contributing to the creation of novel therapeutic agents for the treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 72541-00-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,5,4 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72541-00:
(7*7)+(6*2)+(5*5)+(4*4)+(3*1)+(2*0)+(1*0)=105
105 % 10 = 5
So 72541-00-5 is a valid CAS Registry Number.
72541-00-5Relevant academic research and scientific papers
Total synthesis of (-)-teucvidin
Liu, Xiaozu,Lee, Chi-Sing
, p. 2886 - 2889 (2012/08/07)
A concise enantioselective synthesis of (-)-teucvidin has been achieved. Our synthetic strategy involved the diastereoselective Michael/Conia-ene cascade cyclization reaction for rapid establishment of the cis-decalin skeleton with three new stereogenic centers in one pot (72%, single diastereomer), the epoxidation/dealkoxycarbonylation protocol for construction of the fused furanone moiety, and the O-allylation/Claisen rearrangement protocol for construction of the all-carbon quaternary center at C9 of the clerodane skeleton.
NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM CANADENSE
Bruno, Maurizio,Piozzi, Franco,Savona, Guiseppe,Torre, Maria C. De La,Rodriguez, Benjamin
, p. 3539 - 3541 (2007/10/02)
From the aerial parts of Teucrium canadense two new neo-clerodane diterpenoids, 18-acetylmontanin D and isoteuflin, have been isolated, besides the previously known diterpenes teucvidin, teuflin, teucvin, 12-epiteupolin II, teuscorodal and (12R)-teupolin I.The structures of 18-acetylmontanin D (18-acetoxy-4α,19;15,16-diepoxy-6β-hydroxy-neo-cleroda-13(16),14-dien-20,12S-olide) and isoteuflin (15,16-epoxy-19-nor-neo-cleroda-5(10),13(16),14-triene-18,6β;20,12S-diolide) were established by chemical and spectroscopic means.The isolation of isoteuflin from T. canadense is of biogenetic importance, since it was previously postulated as the intermediate in the biosynthesis of teucvidin and until now only known as a synthetic compound.Key Word Index - Teucrium canadense; Libiatea; diterpenoids; neo-clerodane derivatives.
