72556-74-2

Basic information

• Product Name: PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&
• Synonyms: Phosphocholine chloride tetrahydrate calcium salt purum, >=97.0% (AT);Biocalcose Tetrahydrate;CalciuM Phosphorylcholine Tetrahydrate;Colifos Tetrahydrate;ColincalciuM Tetrahydrate;Epafosforil Tetrahydrate;Fosfocolina Tetrahydrate;Ipercolin Tetrahydrate
• CAS NO: 72556-74-2
• Molecular Formula: C₅H₁₃NO₄P*Ca*Cl*4H₂O
• Molecular Weight: 329.73
• EINECS: 225-403-0
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylcholine Derivatives
• Mol File: 72556-74-2.mol
• Article Data: 1

Chemical Properties

• Appearance: white powder
• Storage Temp.: −20°C
• Water Solubility: Soluble in water
• Stability: Stable, but light sensitive and may also be heat sensitive. Store at -20 C.
• Merck: 14,7362
• BRN: 4835230
• CAS DataBase Reference: PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&(CAS DataBase Reference)
• NIST Chemistry Reference: PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&(72556-74-2)
• EPA Substance Registry System: PHOSPHORYLCHOLINE CHLORIDE CALCIUM SAL&(72556-74-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 72556-74-2(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Phosphocholine Chloride is a specific promoter of heparin and serum β-lipoprotein interaction. Phosphocholine Chloride protected the membranes of platelets, erythrocytes, and lysosomes against the labilizing action of various known membrane labilizers.

InChI:InChI=1/C5H14NO4P.Ca.ClH.4H2O/c1-6(2,3)4-5-10-11(7,8)9;;;;;;/h4-5H2,1-3H3,(H-,7,8,9);;1H;4*1H2/q;+2;;;;;/p-2

Upstream product

• 67-48-1 choline chloride 

Downstream Products

• 4826-71-5 phosphorylcholine chloride, calcium salt 
• 107-73-3 phosphorylcholine chloride 

Relevant articles and documents

A phosphorus chloride calcium salt of alkali acid radical gallbladder method for preparing four hydrate

The invention relates to a method for preparing phosphorylcholine chloride calcium salt tetrahydrate. The method is characterized by consisting of the following steps: (1) dropwise adding a phosphoric acid solution of anhydrous choline chloride into orthophosphoric acid, and reacting at the temperature of 130-180 DEG C, so as to produce phosphorylcholine chloride; (2) enabling a reaction solution to be subjected to neutralization reaction with a proper amount of calcium chloride, calcium carbonate and calcium hydroxide in water; (3) after neutralization reaction, carrying out solid-liquid separation, and refining filter cakes, so as to obtain calcium dihydrogen phosphate or dicalcium phosphate; (4) filtrating a filtrate, obtained through filtrating, with a filter, and then, concentrating and dehydrating; (5) crystallizing a concentrated solution by adding an alcohol solvent, thereby obtaining the product. The method has the advantages that the process flow is simple, waste gases, waste water and waste residues are not generated, and the product quality meets the requirements of crude drug production.