72586-44-8

Basic information

• Product Name: rac-3-(2-cyanophenoxy)-propane-1,2-diol
• CAS NO: 72586-44-8
• Molecular Weight: 193.202
• Mol File: 72586-44-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: rac-3-(2-cyanophenoxy)-propane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: rac-3-(2-cyanophenoxy)-propane-1,2-diol(72586-44-8)
• EPA Substance Registry System: rac-3-(2-cyanophenoxy)-propane-1,2-diol(72586-44-8)

Safety Data

• Hazardous Substances Data: 72586-44-8(Hazardous Substances Data)

Upstream product

• 611-20-1 salicylonitrile 
• 38465-16-6 1,2-epoxy-3-(2-cyanophenyl)propane 
• 96-24-2 3-monochloro-1,2-propanediol 

Downstream Products

• 82019-16-7 4-(2-cyanophenoxymethyl)-1,3,2-dioxathiolane-2-oxide 
• 1054487-93-2 4-(2-cyanophenoxymethyl)-1,3,2-dioxathiolane-2,2-dioxide 
• 1054487-87-4 (2R)-1-(2-cyanophenoxy)-2,3-propanediol 
• 56715-37-8 (2S)-1-(2-cyanophenoxy)-2,3-propanediol 
• 107995-98-2 [(2-cyanophenoxy)methyl]-15-crown-5 

Relevant articles and documents

Chelation-directed remote: Meta -C-H functionalization of aromatic aldehydes and ketones

We disclose herein the development of a versatile 1,2-diol directing template for palladium-catalyzed remote meta-C-H functionalization of aromatic aldehydes and ketones. In situ-generation of acetals and ketals, as well as removal afterwards, makes the C-H bond functionalization process more straightforward and efficient. This also represents the first example of chelation-directed meta-C-H functionalization of aromatic aldehydes and ketones.