72591-33-4Relevant academic research and scientific papers
Oxidation and Alkylation of Spectinomycin Derivatives: Synthesis of Trospectomycin from Spectinomycin
Herrinton, Paul M.,Klotz, Karen L.,Hartley, William M.
, p. 678 - 682 (2007/10/02)
Trospectomycin can be prepared in five steps from spectinomycin.The overall yield of the process is 13.3 percent.The synthesis involves a new oxidation of silyl enol ether 4 to enone 5 by use of an alkyl hydroperoxide.This reaction is mild and very selcti
