56733-83-6

Basic information

• Product Name: 1,3-bis(N-benzyloxycarbonyl)-spectinomycin
• Synonyms: 1,3-bis(N-benzyloxycarbonyl)-spectinomycin
• CAS NO: 56733-83-6
• Molecular Weight: 600.623
• Mol File: 56733-83-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,3-bis(N-benzyloxycarbonyl)-spectinomycin(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(N-benzyloxycarbonyl)-spectinomycin(56733-83-6)
• EPA Substance Registry System: 1,3-bis(N-benzyloxycarbonyl)-spectinomycin(56733-83-6)

Safety Data

• Hazardous Substances Data: 56733-83-6(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 23312-56-3 spectinomycin sulfate tetrahydrate 
• 866941-38-0 2'-O-benzoyl-N,N-bis(benzyloxycarbonyl)-spectinomycin 
• 96699-66-0 Acetic acid (2S,4R,6R)-2-[(1R,2R,3S,4R,5R,6S)-3,5-bis-(benzyloxycarbonyl-methyl-amino)-2,4,6-tris-(2,2,2-trichloro-ethoxycarbonyloxy)-cyclohexyloxy]-6-methyl-3-oxo-tetrahydro-pyran-4-yl ester 
• 96680-98-7 4-O-acetyl-7,9-O-(trichloroethoxycarbonyl)-N,N'-<(benzyloxy)carbonyl>-4(R),4a(R)-tetrahydrospectinomycin 
• 96680-99-8 Carbonic acid (1R,2S,3R,4R,5S,6R)-2,4-bis-(benzyloxycarbonyl-methyl-amino)-6-((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yloxy)-3,5-bis-(2,2,2-trichloro-ethoxycarbonyloxy)-cyclohexyl ester 2,2,2-trichloro-ethyl ester 
• 96681-00-4 4-O-acetyl-N,N'-<(benzyloxy)carbonyl>-4(R)-dihydrospectinomycin 
• 56733-82-5 N,N'-<(benzyloxy)carbonyl>-4(R)-dihydrospectinomycin 
• 1695-77-8 spectinomycin 
• 88824-89-9 (2S,6R)-2,4-bis(benzoyloxy)-6-methyl-2H-pyran-3(6H)-one 
• 88773-23-3 (2R,6R)-2-chloro-4-benzoyloxy-6-methyl-2H-pyran-3-(6H)-one 
• 52080-34-9 1,5-anhydro-2,3,4-tri-O-benzoyl-6-deoxy-D-arabino-hex-1-enitol 

Downstream Products

• 1695-77-8 spectinomycin 
• 78687-56-6 N_.benzyloxycarbonylspectinoic acid methyl ester 
• 88669-04-9 Trospectomycin 
• 103198-47-6 [(4aR,5S,6S,7R,8S,8aR,9aR,10aR)-5-(Benzyloxycarbonyl-methyl-amino)-2-((E)-but-1-enyl)-4a,6,8-trihydroxy-4-oxo-4a,5,6,7,8,8a,9a,10a-octahydro-4H-1,9,10-trioxa-anthracen-7-yl]-methyl-carbamic acid benzyl ester 
• 85951-30-0 Acetic acid (4aS,5S,6S,7R,8S,8aR,9aR,10aR)-5,7-bis-(benzyloxycarbonyl-methyl-amino)-2-((E)-2-dimethylamino-vinyl)-6,8-dihydroxy-4-oxo-5,6,7,8,8a,10a-hexahydro-4H-1,9,10-trioxa-anthracen-4a-yl ester 
• 88625-85-8 Acetic acid (4aS,5S,6R,7R,8S,8aS,9aR,10aR)-5,7-bis-(benzyloxycarbonyl-methyl-amino)-6,8-diformyloxy-2-methyl-4-oxo-5,6,7,8,8a,10a-hexahydro-4H-1,9,10-trioxa-anthracen-4a-yl ester 
• 88625-84-7 Acetic acid (2R,4aR,5S,6R,7R,8S,8aS,9aS,10aR)-4-acetoxy-5,7-bis-(benzyloxycarbonyl-methyl-amino)-6,8-diformyloxy-2-methyl-5,6,7,8,8a,10a-hexahydro-2H-1,9,10-trioxa-anthracen-4a-yl ester 

Relevant articles and documents

Sugar-Pirating as an Enabling Platform for the Synthesis of 4,6-Dideoxyhexoses

An efficient divergent synthetic strategy that leverages the natural product spectinomycin to access uniquely functionalized monosaccharides is described. Stereoselective 2′- and 3′-reduction of key spectinomycin-derived intermediates enabled facile acces

Spectinomycin derivative, preparation method thereof and application of derivative

The invention discloses a spectinomycin derivative, a preparation method thereof and an application of the derivative, and aims to solve the problems of poor mycobacterium-tuberculosis-resistant effect of spectinomycin molecules and the like in prior art, improve target ability of tuberculosis cells, enhance solubility of drugs and relieve toxicity of the drugs for normal cells. According to the spectinomycin derivative, natural amino acid has good biocompatibility and affinity, serves as a carrier and is introduced into the spectinomycin molecules to form a novel spectinomycin derivative by apreparation method of amino protection, carbonyl reduction, amidation and deprotection of spectinomycin. Experimental results show that the antibacterial activity of the spectinomycin derivative formycobacterium tuberculosis is improved, and anti-tuberculous time is prolonged. The spectinomycin derivative has excellent mycobacterium-tuberculosis-resistant activity, so that the spectinomycin derivative has a good application prospect in anti-tuberculous drugs.