726-37-4

Basic information

• Product Name: 2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95
• Synonyms: 2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95;2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95%;N,N-Dimethyl-4-[2-(2-pyridinyl)ethenyl]aniline;N,N-Dimethyl-4-[2-(2-pyridyl)ethenyl]benzenamine
• CAS NO: 726-37-4
• Molecular Formula: C15H16N2
• Molecular Weight: 224.30094
• Product Categories: NLO Chromophores and Intermediates;Non-Linear Optical (NLO) Materials;Photonic and Optical Materials
• Mol File: 726-37-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 135-138 °C (dec.)(lit.)
• Boiling Point: 374.4°C at 760 mmHg
• Flash Point: 180.2°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 8.38E-06mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: 2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95(726-37-4)
• EPA Substance Registry System: 2-(4-(DIMETHYLAMINO)STYRYL)PYRIDINE 95(726-37-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 726-37-4(Hazardous Substances Data)

Usage

General Description

2-(4-(Dimethylamino)styryl)pyridine 95 is a chemical compound commonly used as a fluorescent probe or dye in various scientific applications, including in biochemistry and molecular biology. It is a styryl dye with a pyridine core and a dimethylamino group, giving it fluorescent properties that make it useful for labeling and visualizing biomolecules such as proteins and nucleic acids. Due to its high purity of 95%, it is considered to be a reliable and accurate reagent for research purposes. The compound is often used in fluorescence microscopy, flow cytometry, and other imaging techniques to study biological processes and structures.

InChI:InChI=1/C15H16N2/c1-17(2)15-10-7-13(8-11-15)6-9-14-5-3-4-12-16-14/h3-12H,1-2H3

Upstream product

• 109-06-8 α-picoline 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 4854-85-7 (E)-4-(N,N-dimethylamino)cinnamonitrile 
• 74-86-2 acetylene 
• 1121-60-4 pyridine-2-carbaldehyde 

Relevant articles and documents

First cycloruthenation of 2-alkenylpyridines: synthesis, characterization and properties

Several cyclometalated ruthenium complexes 1-5 with 2-alkenylpyridines as C,N-chelating ligands were synthesized and then characterized by NMR, MS, IR and UV-Vis spectra. According to the single crystal of complex 2, it is evident that carbon from vinyl group is successfully bonded to Ru(ii) center. Moreover, the Ru-N bond trans to the Ru-C bond is elongated (2.127(5) ?), which is consistent with the strong trans effect of the carbon atom compared to that of the nitrogen atom. With different electron-donating groups linked to vinyl, these complexes exhibited regular changes in MLCT absorption bands, which were identified by UV-Vis and CV spectra in combination with DFT and TD-DFT. Interestingly, protonated intermediate species of these complexes in acidic solutions were tracked by the absorption changes and MS spectra, which displayed a possible protonation process of these complexes with the cleavage of Ru-C σ bonds.

Photocatalyzed [2 + 2 + 2]-cycloaddition of nitriles with acetylene: An effective method for the synthesis of 2-pyridines under mild conditions

The photocatalyzed [2 + 2 + 2]-cycloaddition of nitriles with 2 equiv of acetylene to 2-pyridines can be carried out under mild conditions and represents a valuable extension to common synthetical methods. For the ideal wavelength range (350-500 nm), lamps as well as sunlight can be used. Working at room temperature and in organic solvents such as toluene or hexane as well as in water gives satisfying results in many cases. However, it is also possible to vary the solvent and the reaction temperature of the photocatalyzed synthesis and to choose, with respect to the specific substrate, specific requirements for this particular reaction and general requirements of the method. This simple and selective method derives its potential mainly from the large variety of applicable nitriles. Suitable substrates include (functionalized) aliphatic and aromatic nitriles as well as cyanamides derived from secondary amines.