7262-39-7Relevant academic research and scientific papers
A colorimetric and fluorescent chemodosimeter for discriminative and simultaneous quantification of cysteine and homocysteine
Wang, Liguo,Zhou, Qi,Zhu, Baocun,Yan, Liangguo,Ma, Zhenmin,Du, Bin,Zhang, Xiaoling
, p. 275 - 279 (2012)
A highly selective, visible-light-excited and OFF-ON fluorescent chemodosimeter 1 employed conjugate addition/cyclization sequence mechanism, was designed and synthesized to discriminatively detect cysteine (Cys) and homocysteine (Hcy). The addition of Cys and Hcy resulted in the color of the solution of 1 changing from colorless to green under the simulation of physiological condition, and 1 could serve as a naked-eye indicator. Our chemodosimeter can detect Cys and Hcy quantitatively by fluorescence spectrometry method with a detection limit of 0.5 μM (for Cys) and 0.8 μM (for Hcy). To the best of our knowledge, 1 is the first visual and visible-light-excited fluorescent indicator for discriminative and simultaneous detection of Cys and Hcy. Furthermore, the mechanism of the reaction between 1 and Cys was confirmed using ESI-MS and fluorescence spectra.
Fluorescent probe for rapidly detecting hydrazine compounds as well as synthesis and application of fluorescent probe
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Paragraph 0038; 0041, (2021/12/07)
The invention relates to the technical field of fluorescent probes, in particular to a fluorescent probe for rapidly detecting hydrazine compounds, the fluorescent probe comprises A-1 and A-2, and the invention discloses a synthesis method of the fluorescent probe for rapidly detecting the hydrazine compounds. The invention further discloses application of the fluorescent probe for rapidly detecting the hydrazine compounds, and the application comprises a detection method. The probe can quickly respond to hydrazine, hydrazine sulfate, hydrazine nitrate and unsymmetrical dimethylhydrazine, fluorescence enhancement is remarkable, the detection limit is low, and meanwhile high anti-interference performance and selectivity are achieved.
A fluorescein-based probe with high selectivity to cysteine over homocysteine and glutathione
Wang, Huilin,Zhou, Guodong,Gai, Hongwei,Chen, Xiaoqiang
supporting information, p. 8341 - 8343 (2012/10/29)
A fluorescent probe based on fluorescein displays excellent selectivity and sensitivity for cysteine and its application for bio-imaging is described.
