72632-65-6

Basic information

• Product Name: 5-Thiazolamine, 4-methyl-
• Synonyms: 5-Thiazolamine, 4-methyl-;4-Methylthiazol-5-aMine(5-ThiazolaMine, 4-Methyl- );4-Methylthiazol-5-aMine
• CAS NO: 72632-65-6
• Molecular Formula: C₄H₆N₂S
• Molecular Weight: 114.17
• Mol File: 72632-65-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 91 °C(Solv: dichloromethane (75-09-2))
• Boiling Point: 232.5±20.0 °C(Predicted)
• Appearance: /
• Density: 1.258±0.06 g/cm3(Predicted)
• PKA: 5.38±0.10(Predicted)
• CAS DataBase Reference: 5-Thiazolamine, 4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolamine, 4-methyl-(72632-65-6)
• EPA Substance Registry System: 5-Thiazolamine, 4-methyl-(72632-65-6)

Safety Data

• Hazardous Substances Data: 72632-65-6(Hazardous Substances Data)

Usage

Uses

4-methylthiazol-5-amine (cas# 72632-65-6) is a useful reagent in research for preparation method of 5-?aminothiazole non-?steroidal compounds as anti-?inflammatory agents.

Upstream product

• 3696-36-4 2-methylmalononitrile 

Relevant articles and documents

5-aminothiazole non-steroidal anti-inflammatory compound as well as preparation method and application thereof

The invention discloses a 5-aminothiazole non-steroidal anti-inflammatory compound. The compound which is efficient, low in toxicity and small in side effect is prepared from an ester intermediate containing a thiazine ring and a 5-aminothiazole derivative through a transesterification reaction. The preparation method of the compound is simple, the compound has the active groups of the existing non-steroidal anti-inflammatory medicine; meanwhile, the special change of the nitrogen atom position is also designed; compared with the existing non-steroidal anti-inflammatory medicines, the compoundhas better anti-inflammatory and analgesic effects, particularly has good curative effects on arthritis, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, soft tissue inflammation and thelike, has small toxic and side effects on human bodies, and has a very wide market prospect.