72638-68-7Relevant academic research and scientific papers
PREPARATION OF ENANTIOMERICALLY PURE 1-HYDROXY-NEOCEMBRENES TO DETERMINE THE UNSOLVED ABSOLUTE CONFIGURATION OF CEMBRENOIDS
Aoki, Mario,Uyehara, Tadao,Kato, Tadahiro,Kabuto, Kuninobu,Yamaguchi, Shozo
, p. 1121 - 1124 (2007/10/02)
Cis and trans 1-hydroxy-neocembrenes were prepared in an enantiomerically pure form by reduction of dl-ketone with respective (+)- and (-)-Darvon-LiAlH4 complex followed by purification with the aids of esterification with d- and l-menthoxyacetyl chlorides and (-)-camphanic acid chloride, respectively.Absolute configuration of naturally occurring (+)-mayol and (+)-cembrenene was determined by correlation with enantiomerically pure compounds.
