72676-70-1 Usage
Uses
Used in Anticancer Applications:
Nimustine is used as an anticancer agent for the treatment of brain tumors, including gliomas and glioblastomas. It is also utilized in the treatment of certain types of lymphomas and metastatic melanoma. The drug works by damaging the DNA of cancer cells, which inhibits their ability to replicate and ultimately leads to cell death.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, nimustine is used as a component in the development of cancer treatment regimens. Its alkylating properties make it a valuable asset in the fight against various types of cancer, and ongoing research is being conducted to explore its potential in combination therapies for an even broader range of cancer types.
Used in Oncology Research:
Nimustine is also used in oncology research to study the effects of alkylating agents on cancer cells and to develop new treatment strategies. Its role in combination therapies is of particular interest, as it may enhance the efficacy of other chemotherapeutic drugs and improve patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 72676-70-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,7 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72676-70:
(7*7)+(6*2)+(5*6)+(4*7)+(3*6)+(2*7)+(1*0)=151
151 % 10 = 1
So 72676-70-1 is a valid CAS Registry Number.
72676-70-1Relevant academic research and scientific papers
Synthesis and Anticancer Activity of Nitrosourea Derivatives of Phensuximide
Crider, A. Michael,Kolczynski, Thomas M.,Yates, Kathleen M.
, p. 324 - 326 (2007/10/02)
Nitrosourea derivatives 9-13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system antitumor agents.The N-(2-chloroethyl)-N-nitrosourea 13 was active in the mouse ependymoblastoma brain-tumor system, as well as
