72686-12-5

Upstream product

• 7500-53-0 1,2-Phenylenediacetic acid 
• 591-51-5 phenyllithium 

Downstream Products

• 1136077-56-9 (3R,11aS)-11a-diphenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 1136077-46-7 (3R,11aR)-3,11a-diphenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 1365254-17-6 4-phenyl-1,3-dihydro-3-benzazepin-2-one 
• 1365254-18-7 3-benzyl-4-phenyl-1,3-dihydro-3-benzoazepin-2-one 
• 1365254-33-6 3-methyl-4-phenyl-1,3,4,5-tetrahydro-3-benzazepin-2-one 
• 1365254-34-7 3-benzyl-4-phenyl-1,3,4,5-tetrahydro-3-benzazepin-2-one 
• 959260-82-3 3-benzyl-2-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 
• 1136077-63-8 (3S,11aS)-3,11a-diphenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 1136077-65-0 (3S,11aR)-3,11a-diphenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3-b][3]benzazepin-5(6H)-one 
• 1136077-60-5 (S,Z)-1-{α-[N-(2-hydroxy-1-phenylethyl)amino]benzylidene}-indanone 
• 1136077-58-1 (R,Z)-1-{α-[N-(2-hydroxy-1-phenylethyl)amino]benzylidene}-indanone 

Relevant academic research and scientific papers

Synthesis of phenylacetic acids with 2-oxoalkyl substituents in the ortho-position from o-phenylenediacetic acid

A one-step procedure for the synthesis of 2-(2-oxoalkyl)-substituted phenylacetic acids is described. Very slow addition of organolithium compounds to o-phenylenediacetic acid is the crucial feature to obtain the desired ε-oxo acids in good yields. The selective formation of the ε-oxo acids from the diacid is explained on the basis of hemiketal anion formation. Georg Thieme Verlag Stuttgart.