72694-27-0

Upstream product

• 614-16-4 Benzoylacetonitrile 
• 106-49-0 p-toluidine 
• 60375-56-6 (E)-3-amino-3-phenylacrylonitrile 

Downstream Products

• 1071933-27-1 4,4,5,5,6,6,6-heptafluoro-3-oxo-2-[1-phenyl-1-p-tolyl-aminometh-(Z)-ylidene]hexanenitrile 
• 1082467-06-8 5-methyl-2-phenyl-1H-indole-3-carbonitrile 
• 582-78-5 N-(4-methylphenyl)benzamide 
• 72694-07-6 (Z)-2-Cyano-3-phenyl-3-p-tolylamino-dithioacrylic acid ethyl ester 

Relevant academic research and scientific papers

Cobaloxime Catalysis for Enamine Phosphorylation with Hydrogen Evolution

Direct phosphorylation of enamine and enamide with hydrogen evolution was realized via cobaloxime catalysis under visible-light irradiation. Control experiments and spectroscopic studies demonstrated a reductive quenching pathway of cobaloxime catalyst to produce phosphinoyl radical, which underwent cross-coupling with various enamines (and enamides) to give diverse β-phosphinoyl products in good to excellent yields. More interestingly, Z/E mixture of acyclic enamines could convert into single Z-products with good reactivity.

PIDA-mediated oxidative C-C bond formation: Novel synthesis of indoles from n-aryl enamines

A variety of functionalized indoles were synthesized from N-aryl enamines via PIDA-mediated oxidative carbon-carbon bond formation. The features of the present reaction include facilitative preparation of substrates 2, good functional group tolerance, and mild reaction conditions without transition metals.

Modular routes towards new N,O-bidentate ligands containing an electronically delocalised β-enaminone chelating backbone

Polyketones are synthesised by a transition-metal-catalysed copolymerisation of olefins and carbon monoxide. Nickel complexes with N,O-chelating ligands turned out to be promising catalysts in that field. In this work a series of new N,O ligands with an electronically delocalised β-enaminone backbone were synthesised and fully characterised. The ligand design was inspired by the ligand found in the most efficient nickel catalyst for polyketone synthesis and developed to a highly modular LEGO-like arsenal of reactions to versatile substituted β-enaminone ligands. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.