727401-39-0Relevant academic research and scientific papers
New aziridine sulfide ligands for palladium-catalyzed asymmetric allylic alkylation
Braga, Antonio L.,Paix?o, Marcio W.,Milani, Priscila,Silveira, Claudio C.,Rodrigues, Oscar E. D.,Alves, Elenilson F.
, p. 1297 - 1299 (2004)
Aziridine sulfides, a new type of chiral S,N-ligand, have been easily synthesized in a straightforward synthetic route, from an inexpensive and easily available chiral pool. They were used in the Pd-catalyzed asymmetric allylic alkylation of 1,3-diphenyl-2-propenyl acetate with dimethymalonate anion, furnishing the alkylated product in excellent yields and stereo selectivity up to 99%.
