72768-94-6 Usage
Uses
Used in Pharmaceutical Industry:
2-(Difluoromethoxy)benzyl alcohol is used as a pharmaceutical intermediate for its stability and resistance to degradation, which are crucial for the development of new drugs and therapeutic agents. Its organofluorine nature contributes to the compound's potential in enhancing the efficacy and bioavailability of pharmaceutical products.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(Difluoromethoxy)benzyl alcohol is employed as a key building block for the creation of more complex molecules. Its unique properties, such as the presence of the difluoromethoxy group, make it a valuable component in the synthesis of various organic compounds, including potential pharmaceuticals and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 72768-94-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,7,6 and 8 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 72768-94:
(7*7)+(6*2)+(5*7)+(4*6)+(3*8)+(2*9)+(1*4)=166
166 % 10 = 6
So 72768-94-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H8F2O2/c9-8(10)12-7-4-2-1-3-6(7)5-11/h1-4,8,11H,5H2
72768-94-6Relevant academic research and scientific papers
Synthesis of Phenanthridines through Palladium-Catalyzed Cascade Reaction of 2-Halo-N-Ms-arylamines with Benzyl Halides/Sulfonates
Yang, Si-Yi,Han, Wen-Yong,Zhang, Ding-Lei,Zhou, Xiao-Jian,Bai, Mei,Cui, Bao-Dong,Wan, Nan-Wei,Yuan, Wei-Cheng,Chen, Yong-Zheng
, p. 996 - 1003 (2017/02/15)
An efficient palladium-catalyzed nucleophilic substitution/C–H activation/aromatization cascade reaction between readily available 2-halo-N-Ms-arylamines (Ms = methanesulfonyl) and benzyl halides/sulfonates has been described. A wide variety of phenanthridines were synthesized in a one-pot fashion in moderate to high yields (37–86 %). Notably, this method provides a straightforward, facile approach for the synthesis of phenanthridines. The practicality was further substantiated by successfully carrying out a gram-scale preparation.
