72769-03-0

Basic information

• Product Name: 1,3-Benzodioxole, 2,2-difluoro-4-methyl-
• Synonyms: 2,2-difluoro-4-methylbenzo-1,3-dioxole;1,3-Benzodioxole,2,2-difluoro-4-methyl;4-methyl-2,2-difluorobenzodioxole
• CAS NO: 72769-03-0
• Molecular Formula: C8H6F2O2
• Molecular Weight: 172.131
• Mol File: 72769-03-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-Benzodioxole, 2,2-difluoro-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzodioxole, 2,2-difluoro-4-methyl-(72769-03-0)
• EPA Substance Registry System: 1,3-Benzodioxole, 2,2-difluoro-4-methyl-(72769-03-0)

Safety Data

• Hazardous Substances Data: 72769-03-0(Hazardous Substances Data)

Usage

Category

Organic compound

Usage

Production of pharmaceuticals
Production of agrochemicals
Production of other industrial products
Intermediate in the synthesis of other organic compounds

Physical State

Colorless liquid

Boiling Point

High (specific value not provided)

Solvent Properties

Useful as a solvent in various chemical processes

Structural Features

Presence of difluoro groups
Presence of methyl groups

Safety Precautions

Must be handled with proper safety measures due to potential hazards

Upstream product

• 1269252-08-5 4-methylbenzo-1,3-dioxole-2-thione 
• 1583-59-1 2,2-difluoro-1,3-benzodioxole 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 100-39-0 benzyl bromide 
• 531508-58-4 3-(2,2-difluoro-1,3-benzodioxol-4-yl)propyl benzenesulfonate 
• 531508-57-3 2-(2,2-difluoro-1,3-benzodioxol-4-yl)ethyl benzenesulfonate 
• 157437-24-6 (2,2-difluoro-1,3-benzodioxol-4-yl)acetonitrile 

Relevant articles and documents

Pyridine?BrF3, the missing link for clean fluorinations of aromatic derivatives

This work demonstrates the unique features of the never used before Py?BrF3 complex in the field of aromatic organic fluorinations. The main disadvantage of the noncomplexed BrF3 is the fact that usually, in addition to the desired fluorination, a parallel electrophilic aromatic bromination takes place as well. Use of the Py?BrF3 complex reduces this electrophilic bromination, which is observed with most reagents based on fluorine and bromine [BrF].

Circulation-active dioxyalkylenearyl-dihydropyridines

Circulation-active dihydropyridines of the formula STR1 in which R1 is H, CN, NO2 or --COOR7, R7 is H, alkyl or various other radicals, R2 and R4 each independently is alkyl or other radicals, R3 is H or optionally substituted alkyl, and R5 completes a keto or ester group, and physiologically acceptable salts thereof. Also the aldehyde intermediate therefor of the formula STR2