727719-91-7Relevant academic research and scientific papers
Chiral phosphoric acid-catalyzed desymmetrizative glycosylation of 2-deoxystreptamine and its application to aminoglycoside synthesis
Lee, Jeonghyo,Borovika, Alina,Khomutnyk, Yaroslav,Nagorny, Pavel
, p. 8976 - 8979 (2017)
This work describes chiral phosphoric acid (CPA)-catalyzed desymmetrizative glycosylation of meso-diol derived from 2-deoxystreptamine. The chirality of CPA dictates the outcome of the glycosylation reactions, and the use of enantiomeric CPAs results in e
Efficient preparation of a 1,3-diazidocyclitol as a versatile 2-deoxystreptamine precursor
Busscher, Guuske F.,Groothuys, Stan,De Gelder, Rene,Rutjes, Floris P. J. T.,Van Delft, Floris L.
, p. 4477 - 4481 (2007/10/03)
A synthesis route toward 2-deoxystreptamine, a common structure in many of the clinically important aminoglycosides, is presented. Starting from p-benzoquinone and cyclopentadiene, 2-deoxystreptamine is synthesized with key steps involving Pd(0)-catalyzed
