72804-93-4Relevant academic research and scientific papers
Quinolines synthesis by reacting 1,3-butanediol with anilines in the presence of iron catalysts
Khusnutdinov,Bayguzina,Aminov
, p. 1613 - 1618 (2016/08/26)
2-, 4-, 6-, 7-, and 8-substituted quinolines were synthesized in 78–95% yield by the reaction of 1,3- butanediol with anilines in the presence of iron catalysts in carbon tetrachloride.
Synthesis of substituted quinolines by the reaction of anilines with alcohols and CCl4 in the presence of Fe-containing catalysts
Khusnutdinov,Bayguzina,Aminov
, p. 133 - 137 (2013/11/19)
Substituted quinolines were synthesized by the reaction of aniline derivatives with aliphatic alcohols and CCl4 upon the action of the FeCl3·6H2O catalyst.
TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
-
Page/Page column 93, (2012/12/13)
Compounds of Formula I: in which R1, R2, R3, R4 and R10 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by PIM-1 and/or PIM-2 and/or PIM-3 kinases.
Rhodium(I) Complexes of 8-Methyl-, 8-Ethyl-, and 8-Isopropyl-quinolines and Realated 2-Substituted Derivatives
Deeming, Antony J.,Rothwell, Ian P.
, p. 1259 - 1264 (2007/10/02)
The complexes have been prepared from on adding unidentate L (8-methyl-, -ethyl-, or -isopropyl-quinoline) or bidentate L (1,10-phenantroline or quinoline-2-carboxaldehide-N-methylimine). 8-Alkyl-substitution of the latter ligand gives the complexes as isomers with uni- and bi-dentate L respectively with relative stabilities of the unidentate form depending on the 8-substituent in the order Pri > Et > Me.Unidentate L is also favoured by replacing PPh3 by P(C6H11)3 but bidentate co-ordination is found using AsPh3 or PMe2Ph.Equilibrium constants for chloro-bridge cleavage of by 8-substituted and 2,8-disubstituted quinolines are reduced by increasing the size of the 8-susbtituent and even more by further introduction of a 2-methyl group.The contributions of distortions in the co-ordination to these changes in equilibrium constants are discussed.
