7282-02-2

Usage

Uses

Used in Organic Synthesis:
Phenol, 4-iodo-2,3,5-trimethylis used as a reagent in organic synthesis for its unique chemical properties and reactivity, enabling the creation of various complex organic compounds.
Used in Pharmaceutical Production:
As an intermediate, Phenol, 4-iodo-2,3,5-trimethylplays a crucial role in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Dye Manufacturing:
Phenol, 4-iodo-2,3,5-trimethylis utilized in the production of dyes, where its chemical structure imparts specific color characteristics and properties to the final dye products.
Used in Chemical Research and Development:
Phenol, 4-iodo-2,3,5-trimethylis employed in research and development settings to explore its potential applications in various chemical processes and to understand its reactivity and behavior in different chemical environments.
Used in Medicinal Chemistry:
With its potential applications in medicinal chemistry, Phenol, 4-iodo-2,3,5-trimethylis used to develop new pharmaceutical compounds, potentially leading to the discovery of novel treatments and therapies.

Upstream product

• 697-82-5 2,3,5-trimethylphenol 

Downstream Products

• 57362-74-0 4-Octyloxy-2,3,6-trimethyl-iodbenzol 
• 57362-73-9 4-Benzyloxy-2,3,6-trimethyl-1-iodbenzol 
• 845622-80-2 4-acetoxy-N-acetyl-2,3,6-trimethyl-L-tyrosine methyl ester 
• 845622-74-4 methyl (Z)-2-acetamido-3-(4-acetoxy-2,3,6-trimethylphenyl)-propenoate 
• 845622-93-7 2-tert-butoxycarbonylamino-3-(4-hydroxy-2,3,6-trimethyl-phenyl)-propionic acid 
• 845623-07-6 Boc-(2',3',6'-trimethyltyrosine)-Pro-Phe-Phe-NH₂ 
• 126312-58-1 Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate 
• 57362-66-0 4-Benzyloxy-2'-chlor-4'-nitro-2,3,6-trimethyl-biphenyl 
• 845622-68-6 4-iodo-2,3,5-trimethylphenol acetate 

Relevant academic research and scientific papers

A green catalytic method for selective synthesis of iodophenols via aerobic oxyiodination under organic solvent-free conditions

A highly efficient catalytic method for aerobic oxyiodination of various phenols catalysed by copper(II) nitrate was achieved under mild conditions using I2as an iodinating reagent, molecular oxygen as an oxidant, and water as a solvent. The catalyst shows not only high activity for phenols with either electron-donating or electron-withdrawing groups, but also a remarkable selectivity for the formation of para-iodo substituted phenols. This study offers a green method for iodination of aromatic phenols with high atom economy.

Gas-Chromatographic identifi cation of products formed in iodination of methyl phenols by retention indices

Iodination reaction followed by conversion of iodine-substituted methylphenols to the corresponding trifl uoroacetates was suggested for improving the sensitivity of the gas-chromatographic determination of phenol and its methyl-substituted derivatives (al isomers of mono- and diethylphenols, 2,3,5-, 2,3,6-, and 3,4,5-trimethylphenols) in aqueous media. Acylation products of iodo methylphenols (104 compounds) were identifi ed by linear-logarithmic retention indices on a standard nonpolar polydimethylsiloxane stationary phase, and the pattern of their variation with the number and nature of substituents were characterized. A procedure for identifi cation of methyl-substituted phenols in water in their gas-chromatographic determination with an electron-capture detector was developed. Pleiades Publishing, Ltd., 2012.

Development of potent μ-opioid receptor ligands using unique tyrosine analogues of endomorphin-2

Six analogues of tyrosine, which contained alkyl groups at positions 2′, 3′, and 6′, either singly or in combination on the tyramine ring, were investigated for their effect on the opioid activity of [Xaa1]endomorphin-2 (EM-2). The opioid analo

Process for producing 2,6-disubstituted tyrosine

A process for making 2,6-disubstituted tyrosine by the noble metal coupling of a disubstituted aromatic halide or diazonium salt with an amino-protected 2-aminoacrylic acid to form a (Z)-β-(disubstituted phenyl)-α-acylaminoacrylate, and asymmetrically hydrogenating the acrylate to produce the 2,6-disubstituted tyrosine.