126312-58-1

Basic information

• Product Name: Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate
• Synonyms: Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate
• CAS NO: 126312-58-1
• Molecular Weight: 277.32
• Mol File: 126312-58-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate(126312-58-1)
• EPA Substance Registry System: Methyl-(Z)-α-acetamido-β-(2,6-dimethyl-4methoxyphenyl) acrylate(126312-58-1)

Safety Data

• Hazardous Substances Data: 126312-58-1(Hazardous Substances Data)

Upstream product

• 35356-70-8 Methyl 2-acetamidoacrylate 
• 90609-47-5 1-iodo-2,6-dimethyl-4-methoxybenzene 
• 7282-02-2 4-iodo-2,3,5-trimethyl-phenol 
• 6163-58-2 tris-(o-tolyl)phosphine 

Downstream Products

• 126312-59-2 N-Acetyl-2,6-dimethyl-O-methyl-(S)-tyrosine methyl ester 
• 123715-02-6 H-Dmt 

Relevant articles and documents

A convenient asymmetric synthesis of the unnatural amino acid 2,6-dimethyl-L-tyrosine

The title compound was prepared in high optical purity by a five-step synthesis from 3,5-dimethylphenol on a kilogram scale. The key steps were a modified palladium-catalyzed coupling of an aryl iodide with methyl 2-acetamidoacrylate and hydrogenation of the resulting sterically hindered dehydroamino acid 4 using [Rh(1,5-COD)(R,R-DIPAMP)]BF4 as catalyst.