72844-86-1Relevant academic research and scientific papers
Heterogeneous C-H alkenylations in continuous-flow: Oxidative palladium-catalysis in a biomass-derived reaction medium
Ferlin, Francesco,Santoro, Stefano,Ackermann, Lutz,Vaccaro, Luigi
, p. 2510 - 2514 (2017)
Herein we report the unprecedented Fujiwara-Moritani reaction catalysed by the commercially available heterogeneous palladium catalyst Pd/C. The reaction works efficiently in GVL, a biomass derived solvent, in the coupling between variously substituted ac
Aerobic waste-minimized Pd-catalysed C-H alkenylation in GVL using a tube-in-tube heterogeneous flow reactor
Anastasiou, Ioannis,Carpisassi, Luigi,Ferlin, Francesco,Vaccaro, Luigi
supporting information, p. 6576 - 6582 (2021/09/10)
Herein we report the design and application of a tube-in-tube packed-bed flow reactor for the first time for the development of a heterogeneous palladium catalysed oxidative C-C bond formation process. In particular, we have defined an innovative tube-in-
A straightforward synthesis of benzothiazines
Gimbert, Carolina,Vallribera, Adelina
supporting information; experimental part, p. 269 - 271 (2009/08/08)
(Chemical Equation Presented) A series of 4H-3,1-benzothiazines have been successfully synthesized through a three-step sequence starting from commercially available 2-iodoaniline. The key step consists of the cyclization of compounds 6 via an intramolecu
Ortho Vinylation of Aromatic Amides via Cyclopalladation Complexes
Horino, Hiroshi,Inoue, Naoto
, p. 4416 - 4422 (2007/10/02)
The reaction of acetanilide and meta- and para-substituted acetanilides with palladium acetate has given new ortho-palladated complexes 2a-j, which reacted with carbon monoxide, ethylene, or methyl vinyl ketone to produce the corresponding N-acylanthranilic esters 4a-m, 2-acetaminostyrenes 9k-p, and 4-aryl-3-buten-2-one derivatives 9a-j, respectively.Reactions of 2a with substituted olefins proceeded readily to give the 2-olefins 8a-h.Ortho-substituted acetanilides and N-methylacetanilide did not undergo complex formation with palladium acetate.
Photochemical Synthesis. Conversion of o-Vinylthioanilides to Quinolines
Mayo, Paul de,Sydnes, Leiv K.,Wenska, Grazyna
, p. 1549 - 1556 (2007/10/02)
Quinoline derivatives are formed in fair to good yields when acetonitrile solutions of o-vinylthioanilides are irradiated with Pyrex-filtered light.The transformation is a singlet reaction and involves intramolecular cycloaddition of the thioamide, yielding unstable thietanes, as the initial step.In the case of o-(1-trans-propenyl)thioacetanilide (2a) the corresponding thietane has been detected by 1H NMR spectroscopy by irradiating a toluene solution of the compound at -78 deg C.The quantum yield of quinoline formation from 2a appeared to be solvent dependent.Concomitant with quinoline formation, triplet cis-trans isomerization of the vinyl moiety takes place.In the case of 2a the quantum yield for trans -> cis isomerization is 0.506.A variable-temperature 1H NMR study of 2,3-dimethylquinoline in toluene solution has also been performed.For the 2,3-dimethylquinoline-toluene complex the enthalpy and entropy of formation are -1.03 +/- 0.10 kcal/mol and -3.7 +/- 0.2 gibbs/mol, respectively.
