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614-76-6

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614-76-6 Usage

Description

2'-BROMOACETANILIDE is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its reactivity and ability to form derivatives, making it a versatile building block in the chemical and pharmaceutical industries.

Uses

Used in Pharmaceutical Industry:
2'-BROMOACETANILIDE is used as a reagent for the preparation of furan-2-ylmethylene thiazolidinediones, which are novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ. These inhibitors play a crucial role in the development of targeted therapies for various diseases, including cancer and inflammatory disorders, by modulating cellular signaling pathways.
Additionally, 2'-BROMOACETANILIDE may be utilized in other applications within the pharmaceutical industry, such as the synthesis of other bioactive molecules, depending on its specific properties and reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 614-76-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 614-76:
(5*6)+(4*1)+(3*4)+(2*7)+(1*6)=66
66 % 10 = 6
So 614-76-6 is a valid CAS Registry Number.

614-76-6 Well-known Company Product Price

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  • Alfa Aesar

  • (L20132)  2'-Bromoacetanilide, 98+%   

  • 614-76-6

  • 5g

  • 445.0CNY

  • Detail
  • Alfa Aesar

  • (L20132)  2'-Bromoacetanilide, 98+%   

  • 614-76-6

  • 25g

  • 1589.0CNY

  • Detail
  • Aldrich

  • (540633)  2′-Bromoacetanilide  96%

  • 614-76-6

  • 540633-25G

  • 1,826.37CNY

  • Detail

614-76-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromoacetanilide

1.2 Other means of identification

Product number -
Other names N-(2-bromophenyl)acetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:614-76-6 SDS

614-76-6Relevant articles and documents

Ru-Catalyzed C(sp2)?H Bond Arylation of Benzamides Bearing a Novel 4-Aminoantipyrine as a Directing Group

Al Mamari, Hamad H.,Al Kiumi, Diana,Al Rashdi, Tamadher,Al Quraini, Huda,Al Rashdi, Malak,Al Sheraiqi, Sumayya,Al Harmali, Sara,Al Lamki, Mohammed,Al Sheidi, Ahmed,Al Zadjali, Asma

supporting information, p. 3598 - 3603 (2021/07/22)

A novel design-based removable N,O-bidentate directing group based on cheap and commercially available 4-aminoantipyrine (AAP) is reported. Aromatic AP amides bearing 4-aminoantipyrine underwent efficient Ru-catalyzed C(sp2)?H arylation using [RuCl2(PPh3)3] as a catalyst and aryl bromides as electrophiles. The novel bidentate directing group enabled the C?H functionalization reaction with good scope, good functional group tolerance and in decent yields.

Nickel(II)- And Silver(I)-Catalyzed C-H Bond Halogenation of Anilides and Carbamates

Kianmehr, Ebrahim,Afaridoun, Hadi

supporting information, p. 1513 - 1523 (2020/12/14)

ortho -C-H bond halogenation of anilides and N -aryl carbamates using easily available N -halosuccinimides (NXS) as the active halogenation reagent in the presence of nickel or silver catalyst has been developed. This method provides a new approach to 2-haloanilides and carbamates, which may serve as starting materials for the synthesis of pharmaceutically and biologically active compounds.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

Wang, Hao,Wu, Qi,Zhang, Jian-Dong,Li, Hai-Yan,Li, Hong-Xi

supporting information, p. 2078 - 2083 (2021/04/05)

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

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