72848-58-9

Upstream product

• 28752-82-1 2-(allyloxy)benzaldehyde 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 536-57-2 p-toluene sulfinic acid 
• 530-48-3 1,1-Diphenylethylene 
• 118-93-4 o-hydroxyacetophenone 
• 67-68-5 dimethyl sulfoxide 

Relevant academic research and scientific papers

Silver-catalyzed cascade radical cyclization of sodium sulfinates and o-(allyloxy)arylaldehydes towards functionalized chroman-4-ones

An efficient method for the synthesis of functionalized Chroman-4-ones via cascade radical cyclization of sodium sulfinates and o-(allyloxy)arylaldehydes using silver as catalyst and K2S2O8 as oxidant was presented. The de

Selectfluor-Mediated Synthesis of β-Acyl Allyl Sulfones/β-Acyl Allyl Benzotriazoles from Ketones/Acetylenes, Aryl Sulfinates/Benzotriazole, and DMSO as a Dual-Carbon Synthon

A Selectfluor-mediated approach for the synthesis of β-acyl allyl sulfones/β-acyl allyl benzotriazoles with excellent atom economy from readily available acetophenones/aryl acetylenes, aryl sulfinates/benzotriazoles, and dimethyl sulfoxide (DMSO) is described. In this protocol, DMSO acts as a dual-carbon synthon, resulting in a transition-metal-free construction of two C-C and one C-S or two C-C and one C-N bonds in one pot. This approach is extended to generate chemically diverse compounds. Additionally, β-acyl allyl sulfones/β-acyl allyl benzotriazoles were prepared from acetylenes instead of acetophenones.

Synthesis of sulfone-functionalized chroman-4-ones and chromans through visible-light-induced cascade radical cyclization under transition-metal-free conditions

A highly efficient and straightforward approach has been developed for selective intramolecular radical cyclization of arylsulfinic acids with o-(allyloxy)arylaldehydes, o-(homoallyloxy)arylaldehydes and (but-3-en-1-yloxy)benzenes. This photoinduced reaction generated sulfone-functionalized chroman-4-ones and chromans in good to excellent yields under simple and mild conditions without an external photocatalyst.