72850-61-4

Usage

Uses

Used in Pharmaceutical Industry:
2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID is used as a building block for the synthesis of biologically active compounds. Its unique structure and functional groups contribute to the development of novel drug candidates, enhancing the therapeutic potential of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID serves as an intermediate for the production of crop-protection agents. Its properties allow for the creation of innovative compounds that can protect crops from pests and diseases, thereby increasing agricultural productivity.
Used as a Research Tool in Chemical Biology:
2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID is utilized as a research tool in chemical biology, where its unique structure aids in understanding complex biological processes and interactions at the molecular level.
Used as a Research Tool in Medicinal Chemistry:
Similarly, in medicinal chemistry, 2-CHLORO-4-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLIC ACID is employed as a research tool to explore its potential in the development of new therapeutic agents, taking advantage of its chemical properties to probe and modulate biological targets.

Upstream product

• 72850-52-3 ethyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate 
• 72850-53-4 ethyl 2,3-dihydro-2-oxo-4-trifluoromethyl-5-thiazole-carboxylate 
• 344-72-9 ethyl 2-amino-4-(trifluoromethyl)-5-thiazole-carboxylate 

Downstream Products

• 72850-69-2 2-chloro-4-trifluoromethyl-thiazole-5-carboxylic acid phenyl ester 
• 72850-64-7 benzyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate 
• 72860-48-1 2-chloro-4-trifluoromethyl-thiazole-5-carboxylic acid 4-chloro-phenyl ester 
• 72850-71-6 Methyl-2-chlor-4-trifluormethyl-5-thiazolcarboxylat 
• 72850-88-5 Diethylamine Salt of 2-Chloro-4-Trifluoromethyl-5-Thiazolecarboxylic Acid 
• 72850-87-4 Isopropylamine Salt of 2-Chloro-4-Trifluoromethyl-5-Thiazolecarboxylic Acid 

Relevant academic research and scientific papers

Synthesis and Insecticidal Activity of Novel Thiazole Acrylonitrile Derivatives

A series of novel thiazole acrylonitrile derivatives was designed and synthesized utilizing NC-510 as a precursor. Their structures were characterized by NMR spectrometry, MS, and elemental analysis. The results of bioassay indicated that some of these ti

Safened herbicidal sulfonamide compositions

The disclosure herein relates to the use of a variety of antidotal compounds to safen crop plants from the phytotoxicity of azolopyrimidine sulfonamide herbicides.

Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates

A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.

2,4-Disubstituted-5-thiazole-carboxylic acids and derivatives

2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives thereof have been found to reduce herbicidal injury of corn, rice and sorghum plants due to the application thereto of acetamide herbicides.

2,4-Disubstituted-5-thiazole-carboxylic acids and derivatives

2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives thereof have been found to reduce herbicidal injury of corn, rice and sorghum plants due to the application thereto of acetamide herbicides.

2-Chloro-4-trifluoromethyl-5-thiazolecarboxylic acids and derivatives

2-Chloro-4-trifluoromethyl-5-thiazolecarboxylic acids and derivatives thereof have been found to reduce herbicidal injury of sorghum plants due to the application thereto of 2-chloro-N-(2-methoxy-1-methylethyl)-6'-ethyl-o-acetotoluidide.

2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives

2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives thereof have been found to reduce herbicidal injury of corn, rice and sorghum plants due to the application thereto of acetamide herbicides.