72850-52-3

Basic information

• Product Name: ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE
• Synonyms: ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE;2-CHLORO-4-TRIFLUOROMETHYL-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER;Ethyl 2-chloro-4-(trifluoroMethyl)thiazole-5-carboxylate;2-chloro-4-trifluoromethyl-thiazol-5-carboxylic acid-ethyl ester
• CAS NO: 72850-52-3
• Molecular Formula: C₇H₅ClF₃NO₂S
• Molecular Weight: 259.63
• Mol File: 72850-52-3.mol

Chemical Properties

• Melting Point: 57-59
• Boiling Point: 308.7 °C at 760 mmHg
• Flash Point: 140.5 °C
• Appearance: /
• Density: 1.509 g/cm³
• Vapor Pressure: 0.000671mmHg at 25°C
• Refractive Index: 1.481
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -4.03±0.10(Predicted)
• CAS DataBase Reference: ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE(72850-52-3)
• EPA Substance Registry System: ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE(72850-52-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 72850-52-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE is used as an intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical structure and reactivity make it a valuable component in the development of new medications with potential therapeutic benefits.
Used in Agricultural Industry:
In the agricultural sector, ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE serves as an intermediate in the synthesis of agrochemicals. Its incorporation into these compounds can contribute to the development of more effective and targeted pest control solutions, enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
ETHYL 2-CHLORO-4-(TRIFLUOROMETHYL)-1,3-THIAZOLE-5-CARBOXYLATE is used as a building block in the preparation of diverse chemical structures for medicinal chemistry research. Its promising biological properties and versatile reactivity make it a valuable candidate for the discovery and development of novel therapeutic agents.

InChI:InChI=1/C7H5ClF3NO2S/c1-2-14-5(13)3-4(7(9,10)11)12-6(8)15-3/h2H2,1H3

Upstream product

• 344-72-9 ethyl 2-amino-4-(trifluoromethyl)-5-thiazole-carboxylate 
• 363-58-6 ethyl 2-chloro-4,4,4-trifluoro-3-oxobutanoate 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 110-46-3 isopentyl nitrite 
• 72850-53-4 ethyl 2,3-dihydro-2-oxo-4-trifluoromethyl-5-thiazole-carboxylate 
• 141860-78-8 ethyl 3-amino-4,4,4-trifluorocrotonate 
• 2757-23-5 chloro(chlorosulfanyl)methanone 
• 372-29-2 ethyl 3-amino-4,4,4-trifluoro-2-butenoate 

Downstream Products

• 135026-10-7 Ethyl 2-dimethylamino-4-trifluoromethyl-5-thiazolecarboxylate 
• 72850-81-8 Ethyl 2-phenoxy-4-(trifluoromethyl)-5-thiazolecarboxylate 
• 1221786-10-2 ethyl 2-[3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate 
• 72850-88-5 Diethylamine Salt of 2-Chloro-4-Trifluoromethyl-5-Thiazolecarboxylic Acid 
• 72850-87-4 Isopropylamine Salt of 2-Chloro-4-Trifluoromethyl-5-Thiazolecarboxylic Acid 
• 72850-71-6 Methyl-2-chlor-4-trifluormethyl-5-thiazolcarboxylat 
• 78451-00-0 2-Chloro-5-<(benzyloxy)methyl>-4-(trifluoromethyl)thiazole 
• 72860-48-1 2-chloro-4-trifluoromethyl-thiazole-5-carboxylic acid 4-chloro-phenyl ester 
• 72850-64-7 benzyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate 
• 72850-69-2 2-chloro-4-trifluoromethyl-thiazole-5-carboxylic acid phenyl ester 
• 72850-80-7 Ethyl 2-fluoro-4-(trifluoromethyl)-5-thiazolecarboxylate 
• 72850-61-4 2-chloro-4-(trifluoromethyl)-5-thiazolecarboxylic acid 
• 106203-24-1 4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester 
• 78450-97-2 2-Chloro-4-(trifluoromethyl)-5-thiazolemethanol 

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