72851-18-4

Basic information

• Product Name: Pyrazolo[1,5-a]pyrimidine, 7-phenyl-
• CAS NO: 72851-18-4
• Molecular Formula: C12H9N3
• Molecular Weight: 195.224
• Mol File: 72851-18-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyrazolo[1,5-a]pyrimidine, 7-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazolo[1,5-a]pyrimidine, 7-phenyl-(72851-18-4)
• EPA Substance Registry System: Pyrazolo[1,5-a]pyrimidine, 7-phenyl-(72851-18-4)

Safety Data

• Hazardous Substances Data: 72851-18-4(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 274-71-5 pyrazolo[1,5-a]pyrimidine 
• 1820-80-0 3-aminopyrazole 
• 66894-71-1 3-Hydroperoxy-1-phenylpropin-⁽¹⁾ 

Downstream Products

• 72852-01-8 2,2,2-trifluoro-1-(7-phenyl-pyrazolo[1,5-a]pyrimidin-3-yl)-ethanone 

Relevant articles and documents

Catalyst-Switchable Regiocontrol in the Direct Arylation of Remote C-H Groups in Pyrazolo[1,5-a]pyrimidines

The regiodivergent palladium-catalyzed C-H arylation of pyrazolo[1,5-a]pyrimidine has been achieved, wherein the switch in regioselectivity between positions C3 and C7 is under complete catalyst control. A phosphine-containing palladium catalyst promotes the direct arylation at the most acidic position (C7), whereas a phosphine-free catalyst targets the most electron-rich position (C3).

Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines

This disclosure describes substituted pyrazolo[1,5-a]pyrimidines and imidazo[1,5-a]pyrimidines which possess anxiolytic activity.