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72869-16-0

PRAMIRACETAM SULFATE is a nootropic drug belonging to the piracetam family, introduced in 1993 for the treatment of attention and memory disorders resulting from degenerative or vascular disorders in the elderly. It has been observed to reduce depression, anxiety, sleep disturbance, and hostility in patients with mild to moderate primary degenerative dementia, with no observable adverse reactions. Additionally, it has shown significant improvement in memory performance, particularly delayed recall, in patients with brain injury.

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  • 72869-16-0 Structure

  • Basic information

    1. Product Name: PRAMIRACETAM SULFATE
    2. Synonyms: PRAMIRACETAM SULFATE;Pramiracetam sulphate;Amacetam sulfate;CI-879;N-[2-[Bis(1-methylethyl)amino]ethyl]-2-oxo-1-pyrrolidineacetamide sulfate;1-PyrrolidineacetaMide, N-(2-(bis(1-Methylethyl)aMino)ethyl)-2-oxo-;N-[2-(Diisopropylamino)ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide
    3. CAS NO:72869-16-0
    4. Molecular Formula: C14H27N3O2.H2O4S
    5. Molecular Weight: 367.464
    6. EINECS: 615-895-9
    7. Product Categories: Health supplements;APIS;Brain health drug;Nootropic
    8. Mol File: 72869-16-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 461 °C at 760 mmHg
    3. Flash Point: 232.6 °C
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: PRAMIRACETAM SULFATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: PRAMIRACETAM SULFATE(72869-16-0)
    11. EPA Substance Registry System: PRAMIRACETAM SULFATE(72869-16-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 72869-16-0(Hazardous Substances Data)

72869-16-0 Usage

Uses

Used in Pharmaceutical Industry:
PRAMIRACETAM SULFATE is used as a cognition activator and nootropic drug for the treatment of attention and memory disorders in elderly patients with degenerative or vascular disorders. It helps in reducing depression, anxiety, sleep disturbance, and hostility, and improving memory performance, especially delayed recall.
Used in Research and Development:
PRAMIRACETAM SULFATE is used as a cognition adjuvant in research and development for studying its effects on learning and memory enhancement. It has been observed to increase the rate of learning of complex visual discrimination problems in young, normal rhesus monkeys, indicating its potential use in cognitive enhancement therapies.

Originator

Warner-Lambert (U.S.A.)

Check Digit Verification of cas no

The CAS Registry Mumber 72869-16-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,8,6 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 72869-16:
(7*7)+(6*2)+(5*8)+(4*6)+(3*9)+(2*1)+(1*6)=160
160 % 10 = 0
So 72869-16-0 is a valid CAS Registry Number.

72869-16-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[2-[di(propan-2-yl)amino]ethyl]-2-(2-oxopyrrolidin-1-yl)acetamide,sulfuric acid

1.2 Other means of identification

Product number -
Other names PRAMIRACETAM SULFATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72869-16-0 SDS

72869-16-0Downstream Products

72869-16-0Relevant articles and documents

Industrial preparation method of pramiracetam sulfate

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Paragraph 0035; 0052; 0057; 0058; 0059; 0064; 0065; 0070, (2020/04/02)

The invention relates to the field of preparation of compounds, in particular to an industrial preparation method of pramiracetam sulfate. The method includes: (1) converting N-(2-(diisopropyl)ethyl)-2-chloroacetamide hydrochloride to obtain free amide, and removing moisture in the free amide; (2) reacting solid alkali with alpha-pyrrolidone in a solvent I under the protection of nitrogen, simultaneously distilling alcohol generated by the reaction, then adding a solution prepared from the free amide and the solvent I dropwise, and carrying out reaction to obtain pramiracetam; and (3) preparing pramiracetam and sulfuric acid into pramiracetam sulfate. According to the method, pramiracetam sulfate with excellent quality can be efficiently obtained, and the method has the characteristics oflow cost, high environmental friendliness, no use of dangerous materials, and high process safety, and is beneficial to popularization and application in industrial preparation.

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