7287-05-0Relevant articles and documents
Tailoring aqueous solvents for organic reactions: Heck coupling reactions in high temperature water
Gron,Tinsley
, p. 227 - 230 (1999)
High temperature water is demonstrated to be an effective solvent for Heck coupling reactions of aromatic halides with cyclic alkenes without the addition of co-solvents or specialized ligands. Reactions in the presence of LiCl and quaternary ammonium salts indicate that the reaction takes place in the aqueous phase.