Tetrahedron Letters p. 227 - 230 (1999)
Update date:2022-08-04
Topics:
Gron
Tinsley
High temperature water is demonstrated to be an effective solvent for Heck coupling reactions of aromatic halides with cyclic alkenes without the addition of co-solvents or specialized ligands. Reactions in the presence of LiCl and quaternary ammonium salts indicate that the reaction takes place in the aqueous phase.
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