728916-25-4Relevant articles and documents
An image contrast agent selectively activated by prostate specific antigen
Jones, Graham B.,Crasto, Curtis F.,Mathews, Jude E.,Xie, Longfei,Mitchell, Miguel O.,El-Shafey, Ahmed,D'Amico, Anthony V.,Bubley, Glenn J.
, p. 418 - 425 (2007/10/03)
A family of image contrast agent conjugates designed to undergo enzymatic activation has been synthesized. The agents underwent activation both with enzymatically active prostate specific antigen (PSA) and α-chymotrypsin, releasing free fluorophore via cl