728951-37-9Relevant academic research and scientific papers
Arylalkylcarbamate derivatives production and use thereof in therapy
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Page/Page column 8, (2008/06/13)
Compound of the general formula (I) [image] in which n represents an integer ranging from 1 to 7; A is selected from the group consisting of X, Y and Z; X represents a C1-2-alkylene group optionally substituted by one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted by one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Z represents a C3-7-cycloalkyl group of formula: [image] m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen or halogen or a hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-4-fluoroalkyl, C1-4-fluoroalkoxy or C1-4-fluorothioalkyl group; R2 represents a hydrogen or halogen or a cyano, nitro, hydroxyl, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-4-fluoroalkyl, C1-4-fluoroalkoxy, C1-4-fluorothioalkyl group, or an aryl-type or heteroaryl-type group optionally substituted by one or more substituents; R3 represents a group of general formula CHR4CONHR5 in which R4 represents a hydrogen or a C1-3-alkyl group and R5 represents a hydrogen or a C1-3-alkyl, C3-5-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene group; in the form of the base, acid addition salt, hydrate or solvate.
