729-18-0 Usage
General Description
4-Ethoxy-4'-biphenylcarboxylic acid is a chemical compound with the molecular formula C16H14O3. It belongs to the class of biphenylcarboxylic acids and contains two aromatic rings connected by a carboxylic acid group. 4-Ethoxy-4'-biphenylcarboxylic acid is commonly used for its antioxidant and antimicrobial properties and is often used in the production of pharmaceuticals, agrochemicals, and other industrial applications. 4-Ethoxy-4'-biphenylcarboxylic acid is also known for its stability and low toxicity, making it a valuable ingredient in various formulations. Additionally, it has potential applications in the fields of organic synthesis and materials science due to its unique chemical structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 729-18-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,2 and 9 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 729-18:
(5*7)+(4*2)+(3*9)+(2*1)+(1*8)=80
80 % 10 = 0
So 729-18-0 is a valid CAS Registry Number.
729-18-0Relevant articles and documents
Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa
Klein, Scott I.,Czekaj, Mark,Gardner, Charles J.,Guertin, Kevin R.,Cheney, Daniel L.,Spada, Alfred P.,Bolton, Scott A.,Brown, Karen,Colussi, Dennis,Heran, Christopher L.,Morgan, Suzanne R.,Leadley, Robert J.,Dunwiddie, Christopher T.,Perrone, Mark H.,Chu, Valeria
, p. 437 - 450 (2007/10/03)
The discovery and some of the basic structure-activity relationships of a series of novel nonpeptide inhibitors of blood coagulation Factor Xa is described. These inhibitors are functionalized β-alanines, exemplified by 2a. Docking experiments placing 2a in the active site of Factor Xa implied that the most expeditious route to enhancing in vitro potency was to modify the group occupying the S3 site of the enzyme. Increasing the hydrophobic contacts between the inhibitor and the enzyme in this region led to 8, which has served as the prototype for this series. In addition, an enantioselective synthesis of these substituted β-alanines was also developed.
