72902-77-3

Usage

Uses

Used in Fragrance Industry:
(R)-1-(3-Phenoxy-phenyl)-ethanol is used as a fragrance ingredient for its floral, rose-like aroma in various cosmetic and personal care products. It is commonly found in perfumes, colognes, and other scented products, adding a pleasant and distinctive scent to these items.
Used in Pharmaceutical Industry:
(R)-1-(3-Phenoxy-phenyl)-ethanol has potential applications in the pharmaceutical field, although the specific uses are not detailed in the provided materials. Its potential in this industry could be due to its unique chemical structure and properties, which may be harnessed for developing new drugs or drug delivery systems.
Used in Chemical Synthesis:
In addition to its applications in the fragrance and pharmaceutical industries, (R)-1-(3-Phenoxy-phenyl)-ethanol may also be utilized in chemical synthesis. Its specific role in this field is not explicitly mentioned in the materials, but its chemical properties could make it a valuable component in the synthesis of other compounds or materials.

Upstream product

• 94340-15-5 (2R,4R)-4-[1-(3-Phenoxy-phenyl)-ethoxy]-pentan-2-ol 
• 94340-15-5 (2S,4S)-4-[1-(3-Phenoxy-phenyl)-ethoxy]-pentan-2-ol 
• 39515-51-0 3-Phenoxybenzaldehyde 
• 544-97-8 dimethyl zinc(II) 
• 90394-16-4 (4S,6S)-4,6-Dimethyl-2-(3-phenoxy-phenyl)-[1,3]dioxane 
• 94340-12-2 (4R,6R)-4,6-Dimethyl-2-(3-phenoxy-phenyl)-[1,3]dioxane 

Downstream Products

• 69410-05-5 2-(4-Chloro-phenylamino)-3-methyl-butyric acid (R)-1-(3-phenoxy-phenyl)-ethyl ester 

Relevant academic research and scientific papers

Evaluation of enantiopure N-(ferrocenylmethyl)azetidin-2-yl(diphenyl) methanol for catalytic asymmetric addition of organozinc reagents to aldehydes

(Chemical Equation Presented) A facile and practical approach to preparation of enantiopure N-(ferrocenylmethyl)azetidin-2-yl(diphenyl)-methanol was developed from cheap and easily available L-(+)-methionine. Synthetic highlights include the three-step, one-pot construction of the chiral azetidine ring and the development of an improved one-step procedure for the synthesis of the key intermediate L-2-amino-4-bromobutanoic acid. Enantiopure N-(ferrocenylmethyl)azetidin-2-yl(diphenyl)methanol was evaluated for catalytic asymmetric addition of organozinc reagents to aldehydes. The asymmetric ethylation, methylation, arylation, and alkynylation of aldehydes achieved enantioselectivity of up to 98.4%, 94.1%, 99.0%, and 84,6% ee, respectively, in the presence of a catalytic amount of chiral N-(ferrocenylmethyl)azetidin-2- yl(diphenyl)methanol. Our results demonstrated further that the four-membered heterocycle-based backbone was a good potential chiral unit for the catalytic asymmetric induction reaction, and the hindrance of the bulky ferrocenyl group, compared to a phenyl group, played an important role in the enantioselectivities. A possible transition for the catalytic asymmetric addition has been proposed on the basis of the crystal structure of the chiral ligand 3b including two HOAc molecules and previous studies.

ASYMMETRIC SYNTHESIS via CHIRAL ACETAL TEMPLATES. 8. REACTIONS WITH ORGANOMETALLIC REAGENTS

The titanium tetrachloride catalyzed coupling of organometallic reagents with chiral acetals 1 is shown to provide a convenient route for the preparation of a variety of chiral alcohols 4 of high optical purity.