72946-77-1Relevant academic research and scientific papers
Synthesis of methylthio-substituted heterocycles using the complex of trifluoromethanesulfonic anhydride with dimethyl sulfide
Shevchenko,Karpov,Zakurdaev,Nenajdenko,Balenkova
, p. 137 - 143 (2000)
A new method was developed for the electrophilic introduction of methylthio group into a series of aromatic heterocyclic compounds through the hetaryl(dimethyl)sulfonium salts formed in the course of the reaction of the respective heterocycles with the complex of dimethyl sulfide and trifluoromethanesulfonic anhydride. By demethylation with triethylamine it was possible to obtain the methylthio-substituted heterocycles.
ADDITION OF ORGANOMETALLICS TO α,β-UNSATURATED THIOCARBONYL COMPOUNDS. IV. FIVE-MEMBERED SULFUR HETEROCYCLES BY 1,4-ADDITION OF THE CARBENOID ICH2MgCl
Guemas, Jean-Pierre,Villieras, Jean
, p. 299 - 306 (2007/10/02)
2,3-Dihydrothiophenes, 2-arylthiophenes, 2-methylthio-3-arylthiophenes and 2-substituted thiazoles are prepared by 1,4-addition of iodomethylmagnesium chloride with β-aminopropenethiones, methyl β-aminopropenedithioate and thioacylformamidines.
SYNTHESIS OF 2,3-DISUBSTITUTED THIOPHENS VIA METALATED ACETYLENES AND ALLENES
Jong, R. L. P. de,Brandsma, L.
, p. C17 - C20 (2007/10/02)
2,3-Disubstituted thiophen derivatives have been obtained in reasonable yields by treating 2-alkyne- and allene derivatives with butyllithium and potassium t-butoxide in tetrahydrofuran, adding carbon disulfide to the organometallic intermediate and then successively adding t-butyl alcohol, hexamethylphosphoric triamide and methyl iodide.
