72952-89-7Relevant academic research and scientific papers
Reaction of N-chloroamines with carbanions derived from ethyl acetoacetate and diethyl malonate
Zorin,Zainashev,Zorin
, p. 1685 - 1688 (2017/09/25)
Carbanions derived from ethyl 3-oxobutanoate and diethyl malonate reacted with an equimolar amount of N-chloro-N-ethylethanamine, N-chloromorpholine, or N-chloropiperidine to give diethyl 2,3-diacetylbutanedioate and tetraethyl ethane-1,1,2,2-tetracarboxylate in 68–83% yield. The possibility of heterocoupling of ethyl 3-oxobutanoate and diethyl malonate carbanions by the action of N-chloro-N-ethylethanamine and the effect of the molar reactant ratio on the selectivity of oxidative homo- and heterocoupling were studied.
ELECTROCHEMICAL OXIDATIVE DIMERIZATION OF ACETOACETIC AND BENZOYLACETIC ESTERS IN THE PRESENCE OF METAL HALIDES
Elinson, M.N.,Lizunova, T.L.,Nikishin, G.I.
, p. 2213 - 2216 (2007/10/02)
Acetoacetic and benzoylacetic esters dimerize on electrolysis in the presence of metal halide mediators to form 2,5-dioxohexane-3,4-dicarboxylic and 1,4-dioxo-1,4-diphenylbutane-2,3-dicarboxylic esters in yields up to 90percent.Primarily the meso-form of the dimer is produced (up to 90percent) under optimal conditions (NaI, -20 deg C) in acetone and acetonitrile.Diastereomers of the dimer are produced in comparable amounts in methanol and ethanol.
