729596-47-8

Basic information

• Product Name: 3,5-di-O-(4-chlorobenzoyl)-2-C-methyl-D-ribono-γ-lactone
• Synonyms: 3,5-di-O-(4-chlorobenzoyl)-2-C-methyl-D-ribono-γ-lactone
• CAS NO: 729596-47-8
• Molecular Weight: 439.249
• Mol File: 729596-47-8.mol

Chemical Properties

• CAS DataBase Reference: 3,5-di-O-(4-chlorobenzoyl)-2-C-methyl-D-ribono-γ-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-di-O-(4-chlorobenzoyl)-2-C-methyl-D-ribono-γ-lactone(729596-47-8)
• EPA Substance Registry System: 3,5-di-O-(4-chlorobenzoyl)-2-C-methyl-D-ribono-γ-lactone(729596-47-8)

Safety Data

• Hazardous Substances Data: 729596-47-8(Hazardous Substances Data)

Upstream product

• 492-30-8 2-C-methyl-D-ribono-1,4-lactone 
• 122-01-0 4-chloro-benzoyl chloride 

Relevant articles and documents

Facile synthesis of 2-C-methyl-D-arabino-γ-1,4-lactones and mechanism study

In our previous research on the synthesis of 3,5-di-O-benzoyl-2-C-methyl-D-arabino-γ-lactone 4a, the reaction mechanism of DMSO-mediated configuration inversion of C2 hydroxyl group in the lactone was ambiguous. As a follow-up to this research, we used s

Preparation method and intermediate body of (2S, 3R, 4R)-3,5-bis-sustituted-2-deoxy-2-hydroxy-2-methyl-D-ribose-gamma-lactone

The invention relates to a preparation method and an intermediate body of (2S, 3R, 4R)-3,5-bis-sustituted-2-deoxy-2-hydroxy-2-methyl-D-ribose-gamma-lactone. The intermediate body has the structure as shown in formula II. A compound in the formula II serves as the intermediate body for preparing (2S, 3R, 4R)-3,5-bis-sustituted-2-deoxy-2-hydroxy-2-methyl-D-ribose-gamma-lactone, stereoselectivity is good, the yield is high, reaction conditions are mild, raw materials 2-C-methyl-D-ribonic acid-1,4 lactone for preparing the intermediate body are wide in source, preparation is easy, and cost is low.

Process for the preparation of ribofuranose derivatives

The present invention relates to a new process in 3 steps starting from 2-C-methyl-D-ribopentono-1,4-lactone for the preparation of tetra-acyl ribofuranose derivatives of formula (I): useful in the synthesis of nucleotides.

PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES

The present invention relates to a new process in 3 steps starting from 2-C-methyl-D-ribopentono-1,4-lactone for the preparation of tetra-acyl ribofuranose derivatives of Formula (I) useful in the synthesis of nucleotides.