729599-78-4Relevant academic research and scientific papers
N-heterocyclic carbene catalyzed ring expansion of 4-formyl-β-lactams: Synthesis of succinimide derivatives
Li, Gong-Qiang,Li, Yi,Dai, Li-Xin,You, Shu-Li
, p. 3519 - 3521 (2008/02/11)
N-Heterocyclic carbene (NHC) has been employed as an efficient catalyst for ring expansion of 4-formyl-β-lactams, allowing the facile synthesis of succinimide derivatives. This organocatalytic process features readily availability of the catalyst, low cat
Unusual rearrangement of spiro β-lactams to 1,4-diazabicyclo[4,4,0] decanes and 1,4-diazabicyclo[4,3,0]nonanes. Synthesis of conformationally restricted σ-receptor ligands
Macías, Alberto,Alonso, Eduardo,Del Pozo, Carlos,González, Javier
, p. 4657 - 4660 (2007/10/03)
Synthesis of 1,4-diazabicyclo[4,4,0]decanes and 1,4-diazabicyclo[4,3,0] nonanes was achieved by using 4-formyl spiro β-lactams as easily available starting materials. Furthermore, the application of this protocol to the preparation of conformationally res
Diastereoselective [2+2]-cycloaddition reactions of unsymmetrical cyclic ketenes with imines: Synthesis of modified prolines and theoretical study of the reaction mechanism
Macias, Alberto,Alonso, Eduardo,Del Pozo, Carlos,Venturini, Alessandro,Gonzalez, Javier
, p. 7004 - 7012 (2007/10/03)
The synthesis of enantiomerically pure modified proline derivatives was achieved by using spiro β-lactams as starting material that were prepared in turn by the [2+2]-cycloaddition of unsymmetrical cyclic ketenes with optically active imines. A theoretica
