729611-16-9

Upstream product

• 1878-67-7 3-Bromophenylacetic acid 
• 431989-42-3 dimethyl 3-(3-bromophenyl)-2-oxopropanephosphonate 
• 1380347-62-5 ethyl 2-((2-[(2R)-2-((1E,3S)-4-(3',4'-dimethyl-1,1'-biphenyl-3-yl)-3-hydroxy-1-buten-1-yl)-5-oxo-1-pyrrolidinyl]ethyl)thio)-1,3-thiazole-4-carboxylate 
• 1380347-01-2 ethyl (4R,5E,7S)-8-(3-bromophenyl)-7-(tertbutyldimethylsilyloxy)-4-((tert-butyloxycarbonyl)amino)-5-octenoate 
• 1380347-00-1 ethyl (4R,5E,7S)-8-(3-bromophenyl)-7-hydroxy-4-((tert-butyloxycarbonyl)amino)-5-octenoate 
• 597577-65-6 ethyl 2-[(2-oxoethyl)thio]-1,3-thiazole-4-carboxylate 
• 597577-64-5 ethyl 2-[(2,2-diethoxyethyl)thio]-1,3-thiazole-4-carboxylate 
• 494224-49-6 (R)-ethyl 4-(tert-butoxycarbonylamino)-5-oxopentanoate 

Relevant academic research and scientific papers

Synthesis and evaluation of γ-lactam analogs of PGE2 as EP4 and EP2/EP4 agonists

To identify topically effective EP4 agonists and EP2/EP4 dual agonists with excellent subtype selectivity, further optimization of the 16-phenyl ω-chain moiety of the γ-lactam 5-thia prostaglandin E analog and the 2-mercaptothiazole-4-carboxylic acid anal