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2,2,2-Trifluoro-1-(2-chlorophenyl)-1-phenylethanol is a complex organic compound with the molecular formula C14H10ClF3O. It is characterized by the presence of a trifluoromethyl group (CF3), a 2-chlorophenyl group, and a phenyl group attached to a central ethanol (C2H5OH) moiety. This chemical is a colorless to pale yellow liquid with a molecular weight of approximately 282.68 g/mol. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity. The compound is typically synthesized through a series of chemical reactions, such as Friedel-Crafts acylation or nucleophilic substitution, and is used in the preparation of compounds with potential applications in medicine and agriculture.

730-63-2

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730-63-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 730-63-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,3 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 730-63:
(5*7)+(4*3)+(3*0)+(2*6)+(1*3)=62
62 % 10 = 2
So 730-63-2 is a valid CAS Registry Number.

730-63-2Downstream Products

730-63-2Relevant academic research and scientific papers

Gas/Liquid-Phase Micro-Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N-Sulfinylimines

Hirano, Kazuki,Gondo, Satoshi,Punna, Nagender,Tokunaga, Etsuko,Shibata, Norio

, p. 406 - 410 (2019/02/13)

A micro-flow nucleophilic trifluoromethylation of carbonyl compounds using gaseous fluoroform was developed. This method also allows the first micro-flow transformation of N-sulfinylimines into trifluoromethyl amines with excellent diastereoselectivity. To demonstrate the synthetic utility of this micro-flow synthesis, the formal micro-flow synthesis of Efavirenz is described.

METHOD FOR PRODUCING TRIFLUOROMETHYL GROUP-CONTAINING ALCOHOLS

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Paragraph 0029-0031; 0033-0035, (2017/02/02)

PROBLEM TO BE SOLVED: To provide a method for producing CF3 group-containing alcohols useful as production intermediates for medicines and agrochemicals. SOLUTION: The method for producing CF3 group-containing alcohols represented by formula (2) comprises

Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System

Okusu, Satoshi,Hirano, Kazuki,Tokunaga, Etsuko,Shibata, Norio

, p. 581 - 585 (2015/10/20)

Fluoroform (HCF3, HFC-23) is a side product in the manufacture of polytetrafluoroethylene (Teflon). Despite its attractive properties, taming HCF3 for trifluoromethylation is quite problematic owing to its low acidity and the labilit

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