73014-18-3Relevant academic research and scientific papers
Copper-catalyzed synthesis of benzanilides from lignin model substrates 2-phenoxyacetophenones under an air atmosphere
Liu, Xinwei,Zhang, Hongye,Wu, Cailing,Chen, Yu,Yu, Bo,Liu, Zhimin,Liu, Zhenghui
, p. 1223 - 1227 (2018/02/06)
The synthesis of chemicals from biomass-derived compounds is an interesting and challenging topic. In this work, using the lignin-derived 2-phenoxyacetophenones as the feedstock we present a novel approach for the synthesis of benzanilides via the reaction of 2-phenoxyacetophenones with anilines catalyzed by CuCl2 in DMSO at 120 °C under an air atmosphere. This approach has wide scope for 2-phenoxyacetophenones and anilines, and various benzanilides accompanied by the corresponding phenols could be obtained in high yields via changing the 2-phenoxyacetophenones and anilines. The reaction mechanism study indicated that the oxidative cleavage of the C-C bond in 2-phenoxyacetophenones and the formation of a C-N bond occurred simultaneously in the reaction process, resulting in the formation of benzanilides together with phenols.
BCl3-promoted synthesis of benzofurans
Kim, Ikyon,Lee, Sei-Hee,Lee, Sunkyung
scheme or table, p. 6579 - 6584 (2009/04/06)
Lewis acidic nature of boron trichloride (BCl3) to coordinate to the carbonyl functionality was exploited for the synthesis of benzofurans via dehydrative cyclization. This mild and efficient procedure allowed for facile access to a number of h
