73029-31-9Relevant academic research and scientific papers
A novel and efficient synthesis of pyrimido[4,5-d]pyrimidine-2,4,7-trione and pyrido[2,3-d:6,5-d] dipyrimidine-2,4,6,8-tetrone derivatives
Dabiri, Minoo,Arvin-Nezhad, Hamid,Khavasi, Hamid Reza,Bazgir, Ayoob
, p. 1770 - 1774 (2007)
An efficient and direct procedure for the synthesis of pyrimido[4,5-d]pyrimidine-2,4,7-trione derivatives has been described under?microwave-assisted conditions. Reaction of 6-amino-1,3-dimethyluracil with aromatic aldehydes resulted in the formation of p
α-ZrP: A highly efficient catalyst for solvent-free synthesis of pyrimido[5',4':5,6]pyrido[2,3-d]pyrimidinetetraone and 4-arylacridinedione derivatives
Abdolmohammadi, Shahrzad
, p. 465 - 469 (2014/05/20)
A solvent-free approach for the synthesis of a series of pyrimido[5',4':5,61pyrido[2,3-d]pyrimidinetetraone and 4-arylacridinedione derivatives is described herein. These compounds having biological importance were prepared via a condensation reaction of aryl aldehydes, ammonium acetate and active methylene compounds including 1,3-dimethylbarbituric acid or dimedone under solvent-free conditions, using Zr(HPO4)2.H 2O (α-ZrP) as an efficient catalyst. The reusability of catalyst and easier isolation of the products along with high yields of products are the advantages of this eco-friendly and versatile protocol.
