73049-07-7

Basic information

• Product Name: Benzeneethanol, a-(4-hydroxyphenyl)-
• CAS NO: 73049-07-7
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Mol File: 73049-07-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 138 °C
• Boiling Point: 365.1±27.0 °C(Predicted)
• Density: 1.192±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzeneethanol, a-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, a-(4-hydroxyphenyl)-(73049-07-7)
• EPA Substance Registry System: Benzeneethanol, a-(4-hydroxyphenyl)-(73049-07-7)

Safety Data

• Hazardous Substances Data: 73049-07-7(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 103-80-0 phenylacetyl chloride 
• 770-09-2 benzyltrimethylsilane 
• 108-95-2 phenol 
• 722-01-0 phenyl phenylacetate 
• 2491-32-9 1-(4-Hydroxyphenyl)-2-phenylethanone 
• 100-44-7 benzyl chloride 

Downstream Products

• 89122-87-2 4-(4-bromobutoxy)-trans-stilbene 
• 6554-98-9 trans-4-Hydroxystilbene 
• 2491-32-9 1-(4-Hydroxyphenyl)-2-phenylethanone 

Relevant articles and documents

A practical method to stereospecifically synthesize trans-stilbene derivatives

A practical method to stereospecifically synthesize trans-stilbenes was developed via the one-pot benzylation-dehydration reaction of aromatic aldehydes with benzyltrimethylsilane (BTMS), which was driven by tetrabutylammonium fluoride (TBAF) in THF. At the same time a plausible description of the whole process was proposed and the effects of substituted groups on the reaction were investigated. Also this method was employed to synthesize three precursors of natural products with excellent yields, which demonstrated that this method is much efficient and practical in the synthesis of some natural products. A practical method to stereospecifically synthesize trans-stilbenes was developed via the one-pot benzylation-dehydration reaction of aromatic aldehydes with benzyltrimethylsilane, which was driven by tetrabutylammonium fluoride in THF. A plausible description of the whole process was proposed and the effects of substituted groups on the reaction were investigated. This method was employed to synthesize three precursors of natural products with excellent yields. Copyright

Silver catalyzed zinc Barbier reaction of benzylic halides in water

Benzylic chlorides react in aqueous dibasic potassium phosphate under silver catalysis with aromatic aldehydes in the presence of zinc dust to give 1,2-diaryl alcohols in moderate to good yields. Dimerization to bibenzyls and reduction of the halide are important side reactions. A wide range of substituted aromatic and heteroaromatic aldehydes and of substituted benzylic chlorides can be used. Aliphatic aldehydes and ketones are unreactive. A mechanism of two SET on the metal surface is discussed.