73053-97-1Relevant academic research and scientific papers
First reported propylphosphonic anhydride (T3P) mediated Robinson–Gabriel cyclization. Synthesis of natural and unnatural 5-(3-indolyl)oxazoles
Szabó, Tímea,Dancsó, András,ábrányi-Balogh, Péter,Volk, Balázs,Milen, Mátyás
supporting information, p. 1353 - 1356 (2019/04/27)
In the present work, a propylphosphonic anhydride (T3P) assisted Robinson–Gabriel cyclization of N-acyl-β-oxotryptamines for the synthesis of 2-substituted-5-(3-indolyl)oxazoles has been developed. The reactions proceeded smoothly in acetonitri
Identification and isolation of insecticidal oxazoles from Pseudomonas spp.
Grundmann, Florian,Dill, Veronika,Dowling, Andrea,Thanwisai, Aunchalee,Bode, Edna,Chantratita, Narisara,Ffrench-Constant, Richard,Bode, Helge B.
, p. 749 - 752 (2012/07/01)
Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of t
Microwave-assisted regioselective synthesis of 2,4-disubstituted imidazoles: Nortopsentin D synthesized by minimal effort
Fresneda,Molina,Sanz
, p. 218 - 221 (2007/10/03)
A two step regioselective synthesis of 2,4-disubstituted imidazoles based on the reaction of α-azidoacetyl indoles with carboxylic acids in the presence of tertiary phosphines followed by cyclization of the resulting ketoamides by the action of ammonium acetate under microwave irradiation is described. The method has successfully been applied to the synthesis of the antifungal nortopsentin D [2,4-bis(3-indolyl)imidazole].
Synthesis of Oxazolylindole Alkaloids from Tryptamine and Tryptophan by Oxidation with 2,3-Dichloro-5,6-dicyanobenzoquinone
Yoshioka, Tadao,Mohri, Kunihiko,Oikawa, Yuji,Yonemitsu, Osamu
, p. 2252 - 2281 (2007/10/02)
When N-acyl derivatives of tryptamine and L-tryptophan methyl ester were treated with DDQ (2 equiv) in tetrahydrofuran or other anhydrous solvents, four consecutive reactions, dehydrogenation, nucleophilic cyclization, another dehydrogenation, and isomeri
