73053-85-7

Basic information

• Product Name: 1H-Indole,3-[2-(phenylmethyl)-5-oxazolyl]-
• Synonyms: 2-benzyl-5-(1H-indol-3-yl)oxazole;3-(2-Benzyl-oxazol-5-yl)-1H-indole;2-(benzyl)-5-(3-indolyl)oxazole;3-(2-benzyl-oxazol-5-yl)-indole
• CAS NO: 73053-85-7
• Molecular Formula: C18H14N2O
• Molecular Weight: 274.322
• Mol File: 73053-85-7.mol
• Article Data: 12

Chemical Properties

• Melting Point: 174 °C
• Boiling Point: 513.4±43.0 °C(Predicted)
• Density: 1.232±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole,3-[2-(phenylmethyl)-5-oxazolyl]- (CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole,3-[2-(phenylmethyl)-5-oxazolyl]- (73053-85-7)
• EPA Substance Registry System: 1H-Indole,3-[2-(phenylmethyl)-5-oxazolyl]- (73053-85-7)

Safety Data

• Hazardous Substances Data: 73053-85-7(Hazardous Substances Data)

Upstream product

• 61-54-1 tryptamine 
• 103-80-0 phenylacetyl chloride 
• 703-80-0 3-acetylindole 
• 7269-72-9 3-indolylglyoxal 
• 150-30-1 Phenylalanine 
• 103-82-2 phenylacetic acid 
• 192189-07-4 tert-butyl 3-iodo-1H-indol-1-carboxylate 
• 1308379-81-8 C₂₃H₂₂N₂O₃ 
• 1308378-58-6 3-trimethylsilanylethynylindole-1-carboxylic acid tert-butyl ester 
• 140-29-4 phenylacetonitrile 
• 99532-45-3 3-acetyl-1-benzenesulfonylindole 
• 343-94-2 tryptamine hydochloride 
• 19462-24-9 N-phenylacetyltryptamine 
• 120191-50-6 5-(1H-indol-3-yl)oxazole 

Downstream Products

• 1435936-73-4 C₁₈H₁₃ClN₂O 
• 1308379-81-8 C₂₃H₂₂N₂O₃ 

Relevant articles and documents

Indole heterocyclic compound, preparation method thereof and application of indole heterocyclic compound in prevention and treatment of plant diseases

The invention discloses an indole heterocyclic compound as well as a preparation method and application thereof in prevention and treatment of plant diseases. According to the method, indole is reacted with oxalyl chloride to obtain indole oxalyl chloride, then indole oxalyl chloride is reduced by tributylstannane to obtain indole carbonyl acetaldehyde, and finally indole carbonyl acetaldehyde isreacted with a corresponding amino acid under the catalysis of iodine to obtain a compound. The indole heterocyclic compound provided by the invention shows especially excellent plant virus resistingactivity, can well inhibit the tobacco mosaic virus, and also shows broad-spectrum plant pathogenic bacteria resisting activity.

First reported propylphosphonic anhydride (T3P) mediated Robinson–Gabriel cyclization. Synthesis of natural and unnatural 5-(3-indolyl)oxazoles

In the present work, a propylphosphonic anhydride (T3P) assisted Robinson–Gabriel cyclization of N-acyl-β-oxotryptamines for the synthesis of 2-substituted-5-(3-indolyl)oxazoles has been developed. The reactions proceeded smoothly in acetonitri

One-pot total synthesis: The first total synthesis of chiral alkaloid pimprinol A and the facile construction of its natural congeners from amino acids

In this work, we accomplished the first total synthesis of chiral alkaloid pimprinol A and the facile construction of its natural congeners: pimprinine, pimprinethine, pimprinaphine, WS-30581A, WS-30581B, laboradorin 1, uguenenazole, balsoxine, texamine in one-pot from commercially available starting materials including amino acids. Further investigating into the mechanism revealed that this improved transformation was achieved by the integration of iodination, Kornblum oxidation, condensation, decarboxylation, annulation, and oxidation reaction sequence.