73075-49-7 Usage
Uses
Used in Pharmaceutical Industry:
6,7-Dichloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its role in the preparation of novel pyrazolo[1,5-a]pyrazine derivatives makes it a valuable asset in the development of new drugs with potential therapeutic applications.
Used as a Biosynthesis Inhibitor:
In the field of biochemistry and pharmacology, 6,7-Dichloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride is utilized as an inhibitor of Phenylethanolamine N-Methyltransferase, an enzyme involved in the biosynthesis of epinephrine. By inhibiting this enzyme, the compound can potentially be used in the treatment of conditions related to the overproduction or dysregulation of epinephrine, such as certain cardiovascular and neurological disorders.
Used in Drug Development:
6,7-Dichloro-1,2,3,4-tetrahydro-isoquinoline hydrochloride's ability to inhibit epinephrine biosynthesis also makes it a promising candidate for drug development, particularly in the area of central nervous system disorders. Its potential applications in this field could include the development of novel treatments for conditions such as anxiety, depression, and post-traumatic stress disorder, where the regulation of epinephrine levels may play a crucial role in symptom management and improvement.
Check Digit Verification of cas no
The CAS Registry Mumber 73075-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,0,7 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 73075-49:
(7*7)+(6*3)+(5*0)+(4*7)+(3*5)+(2*4)+(1*9)=127
127 % 10 = 7
So 73075-49-7 is a valid CAS Registry Number.
73075-49-7Relevant academic research and scientific papers
HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS
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Page/Page column 29, (2009/05/28)
The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
Method for preparing tetrahydroisoquinolines
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, (2008/06/13)
A method for preparing 1,2,3,4-tetrahydroisoquinolines comprising heating N-halo or hydroxyethyl-N-benzylamines in an aluminum chloride melt at 160°-210°.
