73086-50-7Relevant academic research and scientific papers
Effect of Substituents on the Reaction of Aromatic Amines and Formaldehyde in Acid Medium
Nayar, Mazhuvadyil R. Gopinathan,Francis, Joseph D.
, p. 776 - 780 (2007/10/02)
The kinetics and mechanism of the condensation of N- and C-substituted aromatic amines with formaldehyde in acid medium have been studied using quantitative TLC technique, and the first order rate constants and relative reactivities calculated.In all cases where para-position is free, 4-aminobenzyl alcohols are the initial products.These undergo condensation with amines to give 4-(4-aminobenzyl)anilines.The effect of substituents on the reactivity of amines has been discussed.
