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Dimethyl 3,6-dihydropyridazine-1,2-dicarboxylate is a chemical compound with the molecular formula C7H10N2O4. It is a derivative of pyridazine, a heterocyclic compound consisting of a six-membered ring with two nitrogen atoms. This specific compound features a dihydropyridazine ring, which means it has a double bond reduced to a single bond, and two carboxyl groups (-COOH) attached to the 1 and 2 positions of the ring. The two methyl groups (-CH3) are esterified to the carboxyl groups, making the compound a diester. It is a colorless solid and is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of certain calcium channel blockers.

7309-66-2

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7309-66-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7309-66-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,0 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7309-66:
(6*7)+(5*3)+(4*0)+(3*9)+(2*6)+(1*6)=102
102 % 10 = 2
So 7309-66-2 is a valid CAS Registry Number.

7309-66-2Relevant academic research and scientific papers

Synthesis and Thermal Decomposition of cis-3,4,5,6-Tetrahydropyridazine-3,4-d2. Relative Rates of Rotation, Cleavage, and Closure for Tetramethylene

Dervan, Peter B.,Santilli, Donald S.

, p. 3863 - 3870 (2007/10/02)

The stereospecific syntheses of cis-3,4,5,6-tetrahydropyridazine-3,4-d2 (6) and cis- and trans-cyclobutane-1,2-d2 are reported.The thermal decomposition of cis-3,4,5,6-tetrahydopyridazine (6) (gas phase, 439 deg C) affords 67.1 +/- 0.9percent cis-ethylene-1,2-d2, 16.1 +/- 0.8percent trans-ethylene-1,2-d2, 9.4 +/- 0.4percent cis-cyclobutane-1,2-d2, and 7.4 +/- 0.4percent trans-cyclobutane-1,2-d2.The relative rates of rotation, cleavage, and closure for this 1,2-diazene generated tetramethylene-d2 are k(cleavage)/k(closure) = 2.2 +/- 0.2 and k(rotation)/k(closure) = 12 +/- 3.An extra stereospecific cleavage component (46percent) superimposed on the 1,4-biradical pathway (54percent) from the parent tetrahydropyridazine was found, similar to that observed in the 3,4-dimethyl-3,4,5,6-tetrahydropyridazine thermal reactions.Finally, the experimental data fot the parent 1,4 biradical, tetramethylene, are compared to calculated values in the literature.

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